KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.021 | - |
farnesol | at pH 7.5 and 25°C | Mycobacterium tuberculosis | |
0.036 | - |
cholest-4-en-3-one | at pH 7.5 and 25°C | Mycobacterium tuberculosis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
a methyl-branched lipid + O2 + reduced ferredoxin [iron-sulfur] cluster + H+ | Mycobacterium tuberculosis | the enzyme uses spinach NAD(P)H-dependent ferredoxin reductase and the [2Fe-2S] iron-sulfur protein ferredoxin as an electron transport system | an omega-hydroxy-methyl-branched lipid + H2O + oxidized ferredoxin [iron-sulfur] cluster | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
a methyl-branched lipid + O2 + reduced ferredoxin [iron-sulfur] cluster + H+ | the enzyme uses spinach NAD(P)H-dependent ferredoxin reductase and the [2Fe-2S] iron-sulfur protein ferredoxin as an electron transport system | Mycobacterium tuberculosis | an omega-hydroxy-methyl-branched lipid + H2O + oxidized ferredoxin [iron-sulfur] cluster | - |
? | |
cholest-4-en-3-one + O2 + reduced ferredoxin [iron-sulfur] cluster + H+ | - |
Mycobacterium tuberculosis | ? + H2O + oxidized ferredoxin [iron-sulfur] cluster | - |
? | |
farnesol + O2 + reduced ferredoxin [iron-sulfur] cluster + H+ | - |
Mycobacterium tuberculosis | ? + H2O + oxidized ferredoxin [iron-sulfur] cluster | - |
? | |
geranylgeraniol + O2 + reduced ferredoxin [iron-sulfur] cluster + H+ | - |
Mycobacterium tuberculosis | ? + H2O + oxidized ferredoxin [iron-sulfur] cluster | - |
? | |
additional information | the enzyme shows very low activity towards palmitic acid and 15-methyl-palmitic acid | Mycobacterium tuberculosis | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CYP124 | - |
Mycobacterium tuberculosis |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.195 | - |
cholest-4-en-3-one | at pH 7.5 and 25°C | Mycobacterium tuberculosis | |
0.258 | - |
farnesol | at pH 7.5 and 25°C | Mycobacterium tuberculosis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Mycobacterium tuberculosis |