Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.14.14.9 extracted from

  • Alfieri, A.; Fersini, F.; Ruangchan, N.; Prongjit, M.; Chaiyen, P.; Mattevi, A.
    Structure of the monooxygenase component of a two-component flavoprotein monooxygenase (2007), Proc. Natl. Acad. Sci. USA, 104, 1177-1182.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.14.14.9

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4-hydroxyphenylacetate + NADH + H+ + O2 Acinetobacter baumannii
-
 3,4-dihydroxyphenylacetate + NAD+ + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Acinetobacter baumannii Q6Q272
-
-

Reaction

Reaction Comment Organism Reaction ID
4-hydroxyphenylacetate + FADH2 + O2 = 3,4-dihydroxyphenylacetate + FAD + H2O catalytic mechanism and structure-function relationship, overview Acinetobacter baumannii
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-hydroxyphenylacetate + NADH + H+ + O2
-
 Acinetobacter baumannii 3,4-dihydroxyphenylacetate + NAD+ + H2O
-
 ?
4-hydroxyphenylacetate + NADH + H+ + O2 substrate binding, catalytic mechanism and structure-function relationship, overview Acinetobacter baumannii 3,4-dihydroxyphenylacetate + NAD+ + H2O
-
 ?
additional information the enzyme is a two-component system consisting of a NADH-dependent FMN reductase and a monooxygenase C2, that uses reduced FMN as substrate, structure-function relationship, overview Acinetobacter baumannii ?
-
 ?

Subunits

Subunits Comment Organism
More the enzyme is a two-component system consisting of a NADH-dependent FMN reductase and a monooxygenase C2, that uses reduced FMN as substrate, structure analysis, overview Acinetobacter baumannii

Synonyms

Synonyms Comment Organism
p-hydroxyphenylacetate hydroxylase
-
 Acinetobacter baumannii

Cofactor

Cofactor Comment Organism Structure
FMN involved in reaction step 1 catalyzed by the NADH-dependent FMN reductase enzyme component C1 Acinetobacter baumannii
FMNH2 involved in reaction step 2 catalyzed by the monooxygenase enzyme component C2 Acinetobacter baumannii
NADH
-
 Acinetobacter baumannii