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Literature summary for 1.14.14.88 extracted from

  • Pan, H.; Wang, Y.; Zhang, Y.; Zhou, T.; Fang, C.; Nan, P.; Wang, X.; Li, X.; Wei, Y.; Chen, J.
    Phenylalanine ammonia lyase functions as a switch directly controlling the accumulation of calycosin and calycosin-7-O-beta-D-glucoside in Astragalus membranaceus var. mongholicus plants (2008), J. Exp. Bot., 59, 3027-3037.
    View publication on PubMed
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Application

Application Comment Organism
medicine Astragalus membranaceus var. mongholicus is a medicinal plant in traditional Chinese medicine, the enzyme products calycosin and calycosin-7-O-beta-D-glucoside are two major isoflavones related to the bioactivity of the herb Astragalus mongholicus

Cloned(Commentary)

Cloned (Comment) Organism
PCR-amplification Astragalus mongholicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
formononetin + [reduced NADPH-hemoprotein reductase] + O2 Astragalus mongholicus
-
 calycosin + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Astragalus mongholicus Q2ENF7 var. mongholicus
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
 Astragalus mongholicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
formononetin + [reduced NADPH-hemoprotein reductase] + O2
-
 Astragalus mongholicus calycosin + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Synonyms

Synonyms Comment Organism
I3'H
-
 Astragalus mongholicus
isoflavone 3'-hydroxylase
-
 Astragalus mongholicus

Expression

Organism Comment Expression
Astragalus mongholicus gradual increase (1.8fold) of enzyme expression after low-temperature treatment (4 h 2°C) of plants adapted to 16°C, dramatic increase of expression in warm-treatment plants (16°C to 25°C or from 2°C to 25°C), maximum at h 4 during treatment, higher levels than at low-temperature induction, cold-induced mRNA accumulation is light dependent up

General Information

General Information Comment Organism
physiological function calycosin-7-O-beta-D-glucoside pathway, calycosin and calycosin-7-O-beta-D-glucoside accumulate in whole plants, mainly leaves, in response to low temperature Astragalus mongholicus