Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Homo sapiens | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
52000 | - |
x * 52000, SDS-PAGE, x * 59347, calculated | Homo sapiens |
59347 | - |
x * 52000, SDS-PAGE, x * 59347, calculated | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q02928 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Homo sapiens | - |
liver | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.7 | - |
substrate undecanoic acid, omega-1-hydroxylation, in nmol/min/nmol, pH 7.5, 37°C | Homo sapiens |
1 | - |
substrate lauric acid, omega-1-hydroxylation, in nmol/min/nmol, pH 7.5, 37°C | Homo sapiens |
3 | - |
substrate tridecanoic acid, omega-1-hydroxylation, in nmol/min/nmol, pH 7.5, 37°C | Homo sapiens |
8.5 | - |
substrate tridecanoic acid, omega-hydroxylation, in nmol/min/nmol, pH 7.5, 37°C | Homo sapiens |
12 | - |
substrate undecanoic acid, omega-hydroxylation, in nmol/min/nmol, pH 7.5, 37°C | Homo sapiens |
13.9 | - |
substrate isomyristic acid, omega-hydroxylation, in nmol/min/nmol, pH 7.5, 37°C | Homo sapiens |
14.8 | - |
substrate lauric acid, omega-hydroxylation, in nmol/min/nmol, pH 7.5, 37°C | Homo sapiens |
24.5 | - |
substrate isolauric acid, omega-hydroxylation, in nmol/min/nmol, pH 7.5, 37°C | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
isolauric acid + [reduced NADPH-hemoprotein reductase] + O2 | - |
Homo sapiens | 11-hydroxyisolauric acid + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
isomyristic acid + [reduced NADPH-hemoprotein reductase] + O2 | - |
Homo sapiens | 13-hydroxyisomyristic acid + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
lauric acid + [reduced NADPH-hemoprotein reductase] + O2 | - |
Homo sapiens | 12-hydroxylauric acid + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
additional information | isoform CYP4A11 catalyzes the omega- and omega-1-hydroxylation of various fatty acids | Homo sapiens | ? | - |
? | |
tridecanoic acid + [reduced NADPH-hemoprotein reductase] + O2 | - |
Homo sapiens | 13-hydroxytridecanoic acid + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
undecanoic acid + [reduced NADPH-hemoprotein reductase] + O2 | - |
Homo sapiens | 11-hydroxyundecanoic acid + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 52000, SDS-PAGE, x * 59347, calculated | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
cytochrome P450 4A11 | - |
Homo sapiens |