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Literature summary for 1.14.14.78 extracted from
- Metabolism of arachidonic acid to 20-hydroxy-5,8,11,14-eicosatetraenoic acid by P450 enzymes in human liver: involvement of CYP4F2 and CYP4A11 (1998), J. Pharmacol. Exp. Ther., 285, 1327-1336.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0235 | - |
arachidonic acid | pH and temperature not specified in the publication | Homo sapiens |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| phylloquinone + [reduced NADPH-hemoprotein reductase] + O2 | Homo sapiens | - |
omega-hydroxyphylloquinone + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| kidney | - |
Homo sapiens | - |
| liver | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| arachidonic acid + [reduced NADPH-hemoprotein reductase] + O2 | - |
Homo sapiens | (5Z,8Z,11Z,14Z)-20-hydroxyeicosatetraenoic acid + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
| phylloquinone + [reduced NADPH-hemoprotein reductase] + O2 | - |
Homo sapiens | omega-hydroxyphylloquinone + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CYP4F2 | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADPH | - |
Homo sapiens | |
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