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Literature summary for 1.14.14.63 extracted from
- Cytochrome P450 monooxygenase CYP716A141 is a unique beta-amyrin C-16beta oxidase involved in triterpenoid saponin biosynthesis in Platycodon grandiflorus (2017), Plant Cell Physiol., 58, 874-884 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Saccharomyces cerevisiae | Platycodon grandiflorus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Platycodon grandiflorus | A0A1I9Q5Z0 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| root | - |
Platycodon grandiflorus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| beta-amyrin + [reduced NADPH-hemoprotein reductase] + O2 | - |
Platycodon grandiflorus | maniladiol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |  |
| additional information | enzyme catalyzes the hydroxylation of beta-amyrin at C-16beta, plus further oxidation at C-28 to cochalic acid as a minor reaction | Platycodon grandiflorus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Beta-amyrin 16-oxidase | - |
Platycodon grandiflorus |
| CYP716A141 | - |
Platycodon grandiflorus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| cytochrome P450 | - |
Platycodon grandiflorus |
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Release 2023.1 (January 2023)
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