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Literature summary for 1.14.14.50 extracted from

  • Qu, Y.; Easson, M.L.; Froese, J.; Simionescu, R.; Hudlicky, T.; De Luca, V.
    Completion of the seven-step pathway from tabersonine to the anticancer drug precursor vindoline and its assembly in yeast (2015), Proc. Natl. Acad. Sci. USA, 112, 6224-6229 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.14.14.50

Organism

Organism UniProt Comment Textmining
Catharanthus roseus I1TEM1 cultivar Little Delicata
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Source Tissue

Source Tissue Comment Organism Textmining
epidermis
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 Catharanthus roseus
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leaf
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 Catharanthus roseus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
16-methoxytabersonine + [reduced NADPH-hemoprotein reductase] + O2
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 Catharanthus roseus (3R)-3-hydroxy-16-methoxy-1,2-didehydro-2,3-dihydrotabersonine + [oxidized NADPH-hemoprotein reductase] + H2O
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 ?
tabersonine + [reduced NADPH-hemoprotein reductase] + O2
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 Catharanthus roseus (3R)-3-hydroxy-1,2-didehydro-2,3-dihydrotabersonine + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Synonyms

Synonyms Comment Organism
CYP71D1V2
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 Catharanthus roseus
T3O
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 Catharanthus roseus