Literature summary for 1.14.14.47 extracted from

Wang, Z.; Lawson, R.J.; Buddha, M.R.; Wei, C.; Crane, B.R.; Munro, A.W.; Stuehr, D.J.
Bacterial flavodoxins support nitric oxide production by Bacillus subtilis nitric-oxide synthase (2007), J. Biol. Chem., 282, 2196-2202.

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Organism

Organism	UniProt	Comment	Textmining
Bacillus subtilis	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2 L-arginine + 3 reduced flavodoxin + 4 O2	-	Bacillus subtilis	2 L-citrulline + 2 nitric oxide + 3 oxidized flavodoxin + 4 H2O	overall reaction. Flavodoxins YkuN and YkuP support catalysis as kinetically competent redox partners. When an NADPH-utilizing bacterial flavodoxin reductase is added to reduce YkuP or YkuN, both support nitric oxide synthesis from either L-arginine or N-hydroxyarginine, with YkuN being more efficient	?

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Release 2023.1 (January 2023)