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Literature summary for 1.14.14.45 extracted from

  • Bak, S.; Tax, F.; Feldmann, K.; Galbraith, D.; Feyereisen, R.
    CYP83B1, a cytochrome P450 at the metabolic branch point in auxin and indole glucosinolate biosynthesis in Arabidopsis (2001), Plant Cell, 13, 101-111 .
    View publication on PubMedView publication on EuropePMC
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Inhibitors

Inhibitors Comment Organism Structure
tryptamine competitive Arabidopsis thaliana

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.003
-
 indole-3-acetaldoxime pH 7.6, 28°C Arabidopsis thaliana

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana O65782
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
indole-3-acetaldoxime + O2 + glutathione + [reduced NADPH-hemoprotein reductase]
-
 Arabidopsis thaliana 1-aci-nitro-2-indolyl-ethane + H2O + [oxidized NADPH-hemoprotein reductase]
-
 ?

Synonyms

Synonyms Comment Organism
CYP83B1
-
 Arabidopsis thaliana
cytochrome P450 83B1
-
 Arabidopsis thaliana

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
53
-
 indole-3-acetaldoxime pH 7.6, 28°C Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
cytochrome P450
-
 Arabidopsis thaliana

General Information

General Information Comment Organism
physiological function inactivation of CYP83B1 leads to plants with a phenotype that suggests severe auxin overproduction, whereas CYP83B1 overexpression leads to loss of apical dominance typical of auxin deficit Arabidopsis thaliana