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Literature summary for 1.14.14.32 extracted from

  • Bruno, R.D.; Gover, T.D.; Burger, A.M.; Brodie, A.M.; Njar, V.C.
    17alpha-Hydroxylase/17,20 lyase inhibitor VN/124-1 inhibits growth of androgen-independent prostate cancer cells via induction of the endoplasmic reticulum stress response (2008), Mol. Cancer Ther., 7, 2828-2836.
    View publication on PubMedView publication on EuropePMC
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Application

Application Comment Organism
medicine inhibitors of 17alpha-hydroxylase/17,20 lyase are a new class of anti-prostate cancer agents Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
3beta-hydroxy-17-(1H-benzimidazol-1-yl)androsta-5,16-diene VN/124-1 Homo sapiens
ketoconazole
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
DU-145 cell
-
 Homo sapiens
-
PC-3 cell
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
17alpha-hydroxylase/17,20 lyase
-
 Homo sapiens
CYP17
-
 Homo sapiens