Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
endoplasmic reticulum | - |
Mus musculus | 5783 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
58255 | - |
x * 58255, calculation from nucleotide sequence | Homo sapiens |
58255 | - |
x * 58255, calculation from nucleotide sequence | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 | Mus musculus | CYP7B1 oxysterol 7alpha-hydroxylase pathway synthesizes 25% to 30% of all bile acids | cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O | - |
? | |
cholest-5-ene-3beta,27-diol + NADPH + H+ + O2 | Mus musculus | CYP7B1 oxysterol 7alpha-hydroxylase pathway synthesizes 25% to 30% of all bile acids | cholest-5-ene-3beta,7alpha,27-triol + NADP+ + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O75881 | - |
- |
Mus musculus | Q60991 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | hepatic expression is induced during the third week of life and thereafter exhibits a sexually dimorphic expression pattern in this and other tissues in which expression is higher in the male | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 | - |
Homo sapiens | cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O | - |
? | |
cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 | - |
Mus musculus | cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O | - |
? | |
cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 | CYP7B1 oxysterol 7alpha-hydroxylase pathway synthesizes 25% to 30% of all bile acids | Mus musculus | cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O | - |
? | |
cholest-5-ene-3beta,27-diol + NADPH + H+ + O2 | - |
Homo sapiens | cholest-5-ene-3beta,7alpha,27-triol + NADP+ + H2O | - |
? | |
cholest-5-ene-3beta,27-diol + NADPH + H+ + O2 | - |
Mus musculus | cholest-5-ene-3beta,7alpha,27-triol + NADP+ + H2O | - |
? | |
cholest-5-ene-3beta,27-diol + NADPH + H+ + O2 | CYP7B1 oxysterol 7alpha-hydroxylase pathway synthesizes 25% to 30% of all bile acids | Mus musculus | cholest-5-ene-3beta,7alpha,27-triol + NADP+ + H2O | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 58255, calculation from nucleotide sequence | Homo sapiens |
? | x * 58255, calculation from nucleotide sequence | Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
cytochrome P-450 | - |
Homo sapiens | |
cytochrome P-450 | - |
Mus musculus | |
NADPH | - |
Homo sapiens | |
NADPH | - |
Mus musculus |