Literature summary for 1.14.14.25 extracted from

Shibata, N.; Kawarai, T.; Lee, J.H.; Lee, H.S.; Shibata, E.; Sato, C.; Liang, Y.; Duara, R.; Mayeux, R.P.; St George-Hyslop, P.H.; Rogaeva, E.
Association studies of cholesterol metabolism genes (CH25H, ABCA1 and CH24H) in Alzheimer's disease (2006), Neurosci. Lett., 391, 142-146.

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Cloned(Commentary)

Cloned (Comment)	Organism
DNA and amino acid sequence determnination and analysis, determination of single nucleotide polymorphisms in North American Caucasians and Caribbean Hispanic Alzheimer patients, overview	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
additional information	determination of single nucleotide polymorphisms in North American Caucasians and Caribbean Hispanic Alzheimer patients, overview	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	cholesterol metabolism is important in Alzheimer's disease pathogenesis, the enzyme is a risk factor for Alzheimer's disease, along with cholesterol 25-hydroxylase and ATP-binding cassette transporter A1, overview	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	cholesterol metabolism is important in Alzheimer's disease pathogenesis, the enzyme is a risk factor for Alzheimer's disease, along with cholesterol 25-hydroxylase and ATP-binding cassette transporter A1, overview	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
CH24H	-	Homo sapiens

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Release 2023.1 (January 2023)