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Literature summary for 1.14.14.23 extracted from
- Properties of reconstituted cholesterol 7alpha-hydroxylase system from rat and rabbit liver microsomes (1979), Eur. J. Biochem., 93, 419-426.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Oryctolagus cuniculus | - |
enzyme complex reconstituted from cytochrome P-450, NADPH-cytochrome P-450 reductase | - |
| Rattus norvegicus | - |
enzyme complex reconstituted from cytochrome P-450 and NADPH-cytochrome P-450 reductase | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cholesterol + [reduced NADPH-hemoprotein reductase] + O2 | - |
Rattus norvegicus | 7alpha-hydroxycholesterol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |  |
| cholesterol + [reduced NADPH-hemoprotein reductase] + O2 | - |
Oryctolagus cuniculus | 7alpha-hydroxycholesterol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
| additional information | specificity of reconstituted enzyme system | Rattus norvegicus | ? | - |
? | |
| additional information | specificity of reconstituted enzyme system | Oryctolagus cuniculus | ? | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADPH | - |
Rattus norvegicus | |
| NADPH | - |
Oryctolagus cuniculus | |
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Release 2023.1 (January 2023)
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