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Literature summary for 1.14.14.19 extracted from

  • Mu, W.J.; Wen, H.S.; He, F.; Li, J.F.; Liu, M.; Ma, R.Q.; Zhang, Y.Q.; Hu, J.; Qi, B.X.
    Cloning and expression analysis of the cytochrome P450c17s enzymes during the reproductive cycle in ovoviviparous Korean rockfish (Sebastes schlegeli) (2013), Gene, 512, 444-449.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
genes P450c17-I and P450c17-II, DNA and amino acid sequence determination and analysis, phylogenetic analysis, and quantitative real-time PCR expression analysis Sebastes schlegelii

Organism

Organism UniProt Comment Textmining
Sebastes schlegelii
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 from Shandong coastal area, genes P450c17-I and P450c17-II
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Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein two N-glycosylation sites in P450c17-I, 191NSSY and 282NNTA, and one N-glycosylation site in P450c17-II, 251NSSL Sebastes schlegelii

Source Tissue

Source Tissue Comment Organism Textmining
gonad
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 Sebastes schlegelii
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head kidney
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 Sebastes schlegelii
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kidney
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 Sebastes schlegelii
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additional information enzyme expression pattern during the reproductive cycle in ovoviviparous Korean rockfish, quantitative real-time PCR enzyme tissue expression analysis, overview Sebastes schlegelii
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Synonyms

Synonyms Comment Organism
17alpha-hydroxylase
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 Sebastes schlegelii
cytochrome P450c17
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 Sebastes schlegelii

General Information

General Information Comment Organism
physiological function the enzyme plays a critical role in the production of androgens and estrogens in vertebrates, important role of P450c17-I during shift in steroidogenesis Sebastes schlegelii