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Literature summary for 1.14.14.19 extracted from

  • Shackleton, C.H.; Neres, M.S.; Hughes, B.A.; Stewart, P.M.; Kater, C.E.
    17-Hydroxylase/C17,20-lyase (CYP17) is not the enzyme responsible for side-chain cleavage of cortisol and its metabolites (2008), Steroids, 73, 652-656.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information complete 17-hydroxylase deficiency, 17HD, does not play a role in C19 steroid metabolism, but cortisol-treated 17HD patients cannot produce androstenedione, phenotype, overview Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information CYP17 does not perform side-chain cleavage of cortisol and its metabolites, e.g. 11-oxo-etiocholanolone and 11beta-hydroxyetiocholanolone Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
17-hydroxylase/C17,20-lyase
-
Homo sapiens
CYP17
-
Homo sapiens