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Literature summary for 1.14.14.19 extracted from
- Estrogen receptor-alpha mediates an intraovarian negative feedback loop on thecal cell steroidogenesis via modulation of Cyp17a1 (cytochrome P450, steroid 17alpha-hydroxylase/17,20 lyase) expression (2007), FASEB J., 21, 586-595.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| ovarian follicle | follicles cultured in vitro and lacking estrogen receptor alpha exhibit at late stage a markedly increased expression of steroid 17alpha-hydroxylase and secrete much greater amounts of androstenedione than control. They also exhibit increased testosterone synthesis. Estrogen receptor alpha functions as a repressor of steroid 17alpha-hydroxylase synthesis | Mus musculus | - |
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Release 2023.1 (January 2023)
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