Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.14.14.18 extracted from

  • Chen, M.; Regan, R.F.
    Time course of increased heme oxygenase activity and expression after experimental intracerebral hemorrhage: correlation with oxidative injury (2007), J. Neurochem., 103, 2015-2021.
    View publication on PubMed
Search for more literature for 1.14.14.18

Activating Compound

Activating Compound Comment Organism Structure
additional information striatal blood injection increases HO activity, and oxidative stress induces the enzyme, overview Mus musculus

Application

Application Comment Organism
analysis glial HO-1 expression might be an early marker of non-hemorrhagic cell injury in the striatum, time course of induction, overview Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
heme + AH2 + O2 Mus musculus
-
 biliverdin + Fe2+ + CO + A + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus P14901 retired Swiss-Webster breeder mice
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Mus musculus
-
corpus striatum
-
 Mus musculus
-
glial cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
heme + AH2 + O2
-
 Mus musculus biliverdin + Fe2+ + CO + A + H2O
-
 ?

Synonyms

Synonyms Comment Organism
heme oxygenase-1
-
 Mus musculus
HO-1
-
 Mus musculus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Mus musculus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Mus musculus