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Literature summary for 1.14.14.18 extracted from

  • Muz, B.; Kontny, E.; Marcinkiewicz, J.; Maslinski, W.
    Heme oxygenase-1 participates in the anti-inflammatory activity of taurine chloramine (2008), Amino Acids, 35, 397-402.
    View publication on PubMed
Search for more literature for 1.14.14.18

Activating Compound

Activating Compound Comment Organism Structure
additional information hemin and taurine chloramine, Tau-Cl, raise the transcription of the gene encoding HO-1 Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
HO-1 expression analysis by real-time PCR Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
zinc(II) deuteroporphyrin IX-2, 4-bisethyleneglycol
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
heme + AH2 + O2 Homo sapiens HO-1 induction in vivo inhibits cytokine production in synovial tissue, while HO-1 inhibition restores it, overview biliverdin + Fe2+ + CO + A + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P09601
-
-

Source Tissue

Source Tissue Comment Organism Textmining
rheumatoid arthritis fibroblast-like synoviocyte
-
 Homo sapiens
-
synovial tissue obtained from the knee joints at the time of joint surgery or synovectomy, performed as a normal part of clinical care, from 20 rheumatoid arthritis patients, HO-1 expression analysis Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
heme + AH2 + O2
-
 Homo sapiens biliverdin + Fe2+ + CO + A + H2O
-
 ?
heme + AH2 + O2 HO-1 induction in vivo inhibits cytokine production in synovial tissue, while HO-1 inhibition restores it, overview Homo sapiens biliverdin + Fe2+ + CO + A + H2O
-
 ?

Synonyms

Synonyms Comment Organism
heme oxygenase-1
-
 Homo sapiens
HO-1
-
 Homo sapiens