Literature summary for 1.14.14.173 extracted from

Xun, L.; Webster, C.M.
A monooxygenase catalyzes sequential dechlorinations of 2,4,6-trichlorophenol by oxidative and hydrolytic reactions (2004), J. Biol. Chem., 279, 6696-6700 .

Search for more literature for 1.14.14.173

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2,4,6-trichlorophenol + FADH2 + O2	Cupriavidus necator	-	2,6-dichloro-1,4-benzoquinone + Cl- + FAD + H2O	-	?
2,4,6-trichlorophenol + FADH2 + O2	Cupriavidus necator JMP134	-	2,6-dichloro-1,4-benzoquinone + Cl- + FAD + H2O	-	?
2,6-dichlorohydroquinone + FADH2 + O2	Cupriavidus necator	-	2-chloro-6-hydroxy-1,4-benzoquinone + Cl- + FAD + H2O	-	?
2,6-dichlorohydroquinone + FADH2 + O2	Cupriavidus necator JMP134	-	2-chloro-6-hydroxy-1,4-benzoquinone + Cl- + FAD + H2O	-	?

Organism

Organism	UniProt	Comment	Textmining
Cupriavidus necator	-	-	-
Cupriavidus necator JMP134	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2,4,6-trichlorophenol + FADH2 + O2	-	Cupriavidus necator	2,6-dichloro-1,4-benzoquinone + Cl- + FAD + H2O	-	?
2,4,6-trichlorophenol + FADH2 + O2	-	Cupriavidus necator JMP134	2,6-dichloro-1,4-benzoquinone + Cl- + FAD + H2O	-	?
2,6-dichlorohydroquinone + FADH2 + O2	-	Cupriavidus necator	2-chloro-6-hydroxy-1,4-benzoquinone + Cl- + FAD + H2O	-	?
2,6-dichlorohydroquinone + FADH2 + O2	-	Cupriavidus necator JMP134	2-chloro-6-hydroxy-1,4-benzoquinone + Cl- + FAD + H2O	-	?
2,6-dichlorophenol + FADH2 + O2	-	Cupriavidus necator	2,6-dichlorohydroquinone + FAD + H2O	-	?
2,6-dichlorophenol + FADH2 + O2	-	Cupriavidus necator JMP134	2,6-dichlorohydroquinone + FAD + H2O	-	?

Synonyms

Synonyms	Comment	Organism
2,4,6-TCP 4-monooxygenase	-	Cupriavidus necator
2,4,6-trichlorophenol 4-monooxygenase	-	Cupriavidus necator
tcpA	-	Cupriavidus necator

Cofactor

Cofactor	Comment	Organism	Structure
FADH2	-	Cupriavidus necator
NADH	-	Cupriavidus necator

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)