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Literature summary for 1.14.14.16 extracted from
- Phytoestrogen resveratrol suppresses steroidogenesis by rat adrenocortical cells by inhibiting cytochrome P450 c21-hydroxylase (2005), Horm. Res., 64, 280-286.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| resveratrol | decreases adrenal enzyme expression in vivo and in cell culture. Corticosterone production is inhibited 47% by 0.05 mM resveratrol in vitro and 20% ex vivo, while progesterone production is elevated to 400% of control in vitro | Rattus norvegicus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| adrenal cortex | - |
Rattus norvegicus | - |
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Release 2023.1 (January 2023)
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