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Literature summary for 1.14.14.156 extracted from

  • Zhao, Y.; Hull, A.; Gupta, N.; Goss, K.; Alonso, J.; Ecker, J.; Normanly, J.; Chory, J.; Celenza, J.
    Trp-dependent auxin biosynthesis in Arabidopsis: Involvement of cytochrome P450s CYP79B2 and CYP79B3 (2002), Genes Dev., 16, 3100-3112.
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
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-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-tryptophan + 2 [reduced NADPH-hemoprotein reductase] + 2 O2
-
 Arabidopsis thaliana (E)-indol-3-ylacetaldoxime + 2 [oxidized NADPH-hemoprotein reductase] + CO2 + 3 H2O
-
 ?

Synonyms

Synonyms Comment Organism
CYP79B2
-
 Arabidopsis thaliana
CYP79B3
-
 Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Arabidopsis thaliana

General Information

General Information Comment Organism
malfunction cyp79B2/cyp79B3 double mutant has reduced levels of indole-3-acetic acid, shows growth defects consistent with partial auxin deficiency, and is hypersensitive to 5-methyltryptophan Arabidopsis thaliana
physiological function CYP79B2 and CYP79B3 are critical enzymes in auxin biosynthesis in vivo and play critical roles in indole-3-acetic acid biosynthesis Arabidopsis thaliana