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Literature summary for 1.14.14.143 extracted from

  • Mahmoud, S.S.; Croteau, R.B.
    Menthofuran regulates essential oil biosynthesis in peppermint by controlling a downstream monoterpene reductase (2003), Proc. Natl. Acad. Sci. USA, 100, 14481-14486.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.14.14.143

Cloned(Commentary)

Cloned (Comment) Organism
gene mfs, expression under control of the CaMV 35S promoter in transformed peppermint plants Mentha x piperita

Protein Variants

Protein Variants Comment Organism
additional information overexpression and cosuppression of mfs results in the respective increase or decrease in the production of menthofuran Mentha x piperita

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Mentha x piperita
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(+)-pulegone + [reduced NADPH-hemoprotein reductase] + O2 Mentha x piperita pathways for monoterpene biosynthesis in peppermint, overview (+)-menthofuran + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
additional information Mentha x piperita regulation of pulegone metabolism involves menthofuran, the flux of (+)-pulegone through pulegone reductase correlates negatively with the essential oil content of menthofuran, such that menthofuran, and pulegone increase, or decrease, in concert, overview, although (+)-menthofuran does not inhibit (+)-pulegone reductase activity, stem feeding with menthofuran selectively decreases enzyme transcript levels in immature leaves, thereby accounting for decreased reductase activity and increased pulegone content, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mentha x piperita
-
 cv. Black Mitcham, gene mfs
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
 Mentha x piperita
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(+)-pulegone + [reduced NADPH-hemoprotein reductase] + O2
-
 Mentha x piperita (+)-menthofuran + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
(+)-pulegone + [reduced NADPH-hemoprotein reductase] + O2 pathways for monoterpene biosynthesis in peppermint, overview Mentha x piperita (+)-menthofuran + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
additional information regulation of pulegone metabolism involves menthofuran, the flux of (+)-pulegone through pulegone reductase correlates negatively with the essential oil content of menthofuran, such that menthofuran, and pulegone increase, or decrease, in concert, overview, although (+)-menthofuran does not inhibit (+)-pulegone reductase activity, stem feeding with menthofuran selectively decreases enzyme transcript levels in immature leaves, thereby accounting for decreased reductase activity and increased pulegone content, overview Mentha x piperita ?
-
 ?

Synonyms

Synonyms Comment Organism
MFS
-
 Mentha x piperita