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Literature summary for 1.14.14.142 extracted from

  • Zhao, P.; Inoue, K.; Kouno, I.; Yamamoto, H.
    Characterization of leachianone G 2''-dimethylallyltransferase, a novel prenyl side-chain elongation enzyme for the formation of the lavandulyl group of sophoraflavanone G in Sophora flavescens Ait. cell suspension cultures (2003), Plant Physiol., 133, 1306-1313.
    View publication on PubMedView publication on EuropePMC
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Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Sophora flavescens 5783
-
additional information subcellular localization of the enzymes involved in the biosynthetic route from naringenin to sophoraflavanone G, overview Sophora flavescens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
8-dimethylallylnaringenin + [reduced NADPH-hemoprotein reductase] + O2 Sophora flavescens the enzyme is crucial for lavandulylated flavanone formation, the enzyme catalyzes the 2'-hydroxylation of 8-DMAN, which is then formed to sophoraflavanone G, pathway overview leachianone G + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Sophora flavescens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
native enzyme partially by microsome preparation Sophora flavescens

Source Tissue

Source Tissue Comment Organism Textmining
cell suspension culture
-
 Sophora flavescens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
8-dimethylallylnaringenin + [reduced NADPH-hemoprotein reductase] + O2
-
 Sophora flavescens leachianone G + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
8-dimethylallylnaringenin + [reduced NADPH-hemoprotein reductase] + O2 the enzyme is crucial for lavandulylated flavanone formation, the enzyme catalyzes the 2'-hydroxylation of 8-DMAN, which is then formed to sophoraflavanone G, pathway overview Sophora flavescens leachianone G + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Synonyms

Synonyms Comment Organism
8-dimethylallylnaringenin 2'-hydroxylase
-
 Sophora flavescens

Cofactor

Cofactor Comment Organism Structure
additional information the enzyme is a cytochrome P450 monooxygenase Sophora flavescens