Literature summary for 1.14.14.14 extracted from

Aversa, A.; Fittipaldi, S.; Bimonte, V.M.; Wannenes, F.; Papa, V.; Francomano, D.; Greco, E.A.; Lenzi, A.; Migliaccio, S.
Tadalafil modulates aromatase activity and androgen receptor expression in a human osteoblastic cell in vitro model (2016), J. Endocrinol. Invest., 39, 199-205 .

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P11511	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
SAOS-2 cell	-	Homo sapiens	-

Expression

Organism	Comment	Expression
Homo sapiens	phosphodiesterase type-5 inhibitor tadalafil inhibits aromatase mRNA and protein expression leading to an increase in testosterone levels in the supernatants	down

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Release 2023.1 (January 2023)