Application | Comment | Organism |
---|---|---|
medicine | comparison of cerebrocortical microvascular responses to the endothelium-dependent vasodilator ACh between male and female wild-type and aromatase knockout (ArKO) mice. Wild-type female mice have significantly greater responses to ACh compared with wild-type males, which is associated with higher aromatase expression in female compared with male cerebral vessels | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | P28649 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | higher aromatase expression in female compared with male cerebral vessels | Mus musculus | - |
General Information | Comment | Organism |
---|---|---|
physiological function | cerebrovascular endothelial aromatase plays an important and sexually dimorphic role in cerebrovascular function | Mus musculus |