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Literature summary for 1.14.14.14 extracted from
- Role of aromatase in sex-specific cerebrovascular endothelial function in mice (2014), Am. J. Physiol. Heart Circ. Physiol., 306, H929-H937 .
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | comparison of cerebrocortical microvascular responses to the endothelium-dependent vasodilator ACh between male and female wild-type and aromatase knockout (ArKO) mice. Wild-type female mice have significantly greater responses to ACh compared with wild-type males, which is associated with higher aromatase expression in female compared with male cerebral vessels | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | P28649 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | higher aromatase expression in female compared with male cerebral vessels | Mus musculus | - |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | cerebrovascular endothelial aromatase plays an important and sexually dimorphic role in cerebrovascular function | Mus musculus |
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Release 2023.1 (January 2023)
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