Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.14.14.139 extracted from

  • Eggertsen, G.; Olin, M.; Andersson, U.; Ishida, H.; Kubota, S.; Hellman, U.; Okuda, K.I.; Bjorkhem, I.
    Molecular cloning and expression of rabbit sterol 12alpha-hydroxylase (1996), J. Biol. Chem., 271, 32269-32275.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
transfection of COS-M6 cells with the coding part of the cDNA Oryctolagus cuniculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-
Oryctolagus cuniculus
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver exclusively expressed in Oryctolagus cuniculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7alpha-hydroxycholest-4-en-3-one + NADPH + H+ + O2
-
Mus musculus 7alpha,12alpha-dihydroxycholest-4-en-3-one + NADP+ + H2O
-
?
7alpha-hydroxycholest-4-en-3-one + NADPH + H+ + O2
-
Rattus norvegicus 7alpha,12alpha-dihydroxycholest-4-en-3-one + NADP+ + H2O
-
?
7alpha-hydroxycholest-4-en-3-one + NADPH + H+ + O2
-
Oryctolagus cuniculus 7alpha,12alpha-dihydroxycholest-4-en-3-one + NADP+ + H2O
-
?

Synonyms

Synonyms Comment Organism
7alpha-hydroxy-4-cholest-3-on3 12alpha-monooxygenase
-
Oryctolagus cuniculus
CYP12
-
Oryctolagus cuniculus
HCO 12alpha-hydroxylase
-
Oryctolagus cuniculus
sterol 12alpha-hydroxylase
-
Oryctolagus cuniculus

Cofactor

Cofactor Comment Organism Structure
cytochrome P-450
-
Oryctolagus cuniculus
NADPH
-
Mus musculus
NADPH
-
Oryctolagus cuniculus