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Literature summary for 1.14.14.139 extracted from

  • Yang, Y.; Eggertsen, G.; Gafvels, M.; Andersson, U.; Einarsson, C.; Bjorkhem, I.; Chiang, J.Y.
    Mechanisms of cholesterol and sterol regulatory element binding protein regulation of the sterol 12alpha-hydroxylase gene (CYP8B1) (2004), Biochem. Biophys. Res. Commun., 320, 1204-1210.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus sterol regulatory element binding proteins 1a and 1c enhance transcription of the CYP8B1 gene through binding to sterol regulatory element. Cholesterol loading reduces sterol regulatory element binding proteins 1 mRNA expression in addition to reducing functional sterol regulatory element binding proteins 1 protein, and results in decreasing CYP8B1 gene transcription ?
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additional information Rattus norvegicus sterol regulatory element binding proteins 1a and 1c enhance transcription of the CYP8B1 gene through binding to sterol regulatory element. Cholesterol loading reduces sterol regulatory element binding proteins 1 mRNA expression in addition to reducing functional sterol regulatory element binding proteins 1 protein, and results in decreasing CYP8B1 gene transcription ?
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Organism

Organism UniProt Comment Textmining
Mus musculus
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Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information sterol regulatory element binding proteins 1a and 1c enhance transcription of the CYP8B1 gene through binding to sterol regulatory element. Cholesterol loading reduces sterol regulatory element binding proteins 1 mRNA expression in addition to reducing functional sterol regulatory element binding proteins 1 protein, and results in decreasing CYP8B1 gene transcription Mus musculus ?
-
?
additional information sterol regulatory element binding proteins 1a and 1c enhance transcription of the CYP8B1 gene through binding to sterol regulatory element. Cholesterol loading reduces sterol regulatory element binding proteins 1 mRNA expression in addition to reducing functional sterol regulatory element binding proteins 1 protein, and results in decreasing CYP8B1 gene transcription Rattus norvegicus ?
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?

Synonyms

Synonyms Comment Organism
sterol 12alpha-hydroxylase CYP8B1
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Mus musculus
sterol 12alpha-hydroxylase CYP8B1
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Rattus norvegicus