Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
lithocholate + [reduced NADPH-hemoprotein reductase] + O2 | Mesocricetus auratus | the male-specific P450 catalyzes the reaction. The pattern of growth hormone secretion is directly responsible for male-specific expression of this gene. STAT 5a and STAT 5b mediates GH-dependent regulation of CYP3A10/6beta-hydroxylase promoter activity | 6beta-hydroxylithocholate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mesocricetus auratus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | male-specific enzyme. The pattern of growth hormone secretion is directly responsible for male-specific expression of this gene | Mesocricetus auratus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
lithocholate + [reduced NADPH-hemoprotein reductase] + O2 | - |
Mesocricetus auratus | 6beta-hydroxylithocholate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
lithocholate + [reduced NADPH-hemoprotein reductase] + O2 | the male-specific P450 catalyzes the reaction. The pattern of growth hormone secretion is directly responsible for male-specific expression of this gene. STAT 5a and STAT 5b mediates GH-dependent regulation of CYP3A10/6beta-hydroxylase promoter activity | Mesocricetus auratus | 6beta-hydroxylithocholate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
3A10/lithocholic acid 6beta-hydroxylase | - |
Mesocricetus auratus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
cytochrome P-450 | - |
Mesocricetus auratus |