Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(E)-1-(1-(4-chlorophenyl)-3-fluoro-4,4-dimethylpent-1-en-2-yl)-1H-1,2,4-triazole | i.e. UNI-F | Arabidopsis thaliana | |
(E)-1-(1-(4-chlorophenyl)-4,4-dimethylpent-1-en-2-yl)-1H-imidazole | i.e. IMI-H | Arabidopsis thaliana | |
(S,E)-1-(1-(4-chlorophenyl)-3-fluoro-4,4-dimethylpent-1-en-2-yl)-1H-imidazole | i.e. IMI-F | Arabidopsis thaliana | |
(S,E)-1-(1-(4-chlorophenyl)-3-methoxy-4,4-dimethylpent-1-en-2-yl)-1H-imidazole | i.e. IMI-OMe | Arabidopsis thaliana | |
(Z)-1-(1-(4-chlorophenyl)-4,4-dimethylpent-1-en-2-yl)-1H-imidazole | - |
Arabidopsis thaliana | |
1-(4-chlorophenyl)-2-(1H-imidazol-1-yl)-4,4-dimethylpentan-1-ol | - |
Arabidopsis thaliana | |
1-(4-chlorophenyl)-2-(1H-imidazol-1-yl)-4,4-dimethylpentan-1-one | - |
Arabidopsis thaliana | |
S-uniconazole | i.e. S-(+)-E-1-(4-chlorophenyl)-4,4-dimethyl-2-(1,2,4-triazo-1-yl)-1-penten-3-ol or UNI-OH, an azole-containing P450 inhibitor and a plant growth retardant, is a strong inhibitor of the enzyme, structure-activity relationship, the main site of action of UNI-OH is suggested to be ent-kaurene oxidase, EC 1.14.13.78, UNI-OH also inhibits brassinosteroid biosynthesis, and alters the level of other plant hormones, such as auxins, cytokinins, ethylene, and abscisic acid, overview | Arabidopsis thaliana | |
UNI-H | - |
Arabidopsis thaliana | |
UNI-OMe | - |
Arabidopsis thaliana |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Arabidopsis thaliana | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(+)-abscisic acid + [reduced NADPH-hemoprotein reductase] + O2 | Arabidopsis thaliana | key enzyme in abscisic acid catabolism | 8'-hydroxyabscisate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(+)-abscisic acid + [reduced NADPH-hemoprotein reductase] + O2 | - |
Arabidopsis thaliana | 8'-hydroxyabscisate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
(+)-abscisic acid + [reduced NADPH-hemoprotein reductase] + O2 | key enzyme in abscisic acid catabolism | Arabidopsis thaliana | 8'-hydroxyabscisate + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ABA 8-hydroxylase | - |
Arabidopsis thaliana |
CYP707A3 | - |
Arabidopsis thaliana |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Arabidopsis thaliana |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.2 | 7.3 | - |
Arabidopsis thaliana |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | inhibition kinetics, computational methods, overview | Arabidopsis thaliana | |
0.0012 | - |
(S,E)-1-(1-(4-chlorophenyl)-3-methoxy-4,4-dimethylpent-1-en-2-yl)-1H-imidazole | pH 7.2-7.3, 30°C, recombinant enzyme | Arabidopsis thaliana | |
0.0027 | - |
S-(+)-uniconazole | pH 7.2-7.3, 30°C, recombinant enzyme | Arabidopsis thaliana | |
0.0086 | - |
UNI-OMe | pH 7.2-7.3, 30°C, recombinant enzyme | Arabidopsis thaliana | |
0.034 | - |
UNI-H | pH 7.2-7.3, 30°C, recombinant enzyme | Arabidopsis thaliana | |
0.034 | - |
(E)-1-(1-(4-chlorophenyl)-3-fluoro-4,4-dimethylpent-1-en-2-yl)-1H-1,2,4-triazole | pH 7.2-7.3, 30°C, recombinant enzyme | Arabidopsis thaliana |