Literature summary for 1.14.14.137 extracted from

Ueno, K.; Yoneyama, H.; Saito, S.; Mizutani, M.; Sakata, K.; Hirai, N.; Todoroki, Y.
A lead compound for the development of ABA 8'-hydroxylase inhibitors (2005), Bioorg. Med. Chem. Lett., 15, 5226-5229.

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Inhibitors

Inhibitors	Comment	Organism	Structure
(+)-8',8'-difluoroabscisate	competitive	Arabidopsis thaliana
(1'S,2'S,6'S*)-(+-)-6-nor-2',3'-dihydro-4'-deoxo-8',8'-difluoro-abscisate	50% inhibition at 0.00063 mM	Arabidopsis thaliana
(1'S,2'S,6'S*)-(+-)-6-nor-2',3'-dihydro-4'-deoxo-abscisate	50% inhibition at 0.00091 mM	Arabidopsis thaliana

Organism

Organism	UniProt	Comment	Textmining
Arabidopsis thaliana	-	-	-

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.00017	-	(+)-8',8'-difluoroabscisate	pH 7.25, 30°C	Arabidopsis thaliana
0.0004	-	(1'S,2'S,6'S*)-(+-)-6-nor-2',3'-dihydro-4'-deoxo-abscisate	pH 7.25, 30°C	Arabidopsis thaliana
0.00041	-	(1'S,2'S,6'S*)-(+-)-6-nor-2',3'-dihydro-4'-deoxo-8',8'-difluoro-abscisate	pH 7.25, 30°C	Arabidopsis thaliana

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Release 2023.1 (January 2023)