Cloned (Comment) | Organism |
---|---|
expressed in Saccharomyces cerevisiae strain YPH500 | Aspergillus fumigatus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
tryprostatin B + [reduced NADPH-hemoprotein reductase] + O2 | Aspergillus fumigatus | - |
6-hydroxytryprostatin B + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
tryprostatin B + [reduced NADPH-hemoprotein reductase] + O2 | Aspergillus fumigatus BM939 | - |
6-hydroxytryprostatin B + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aspergillus fumigatus | B9WZX1 | - |
- |
Aspergillus fumigatus BM939 | B9WZX1 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
tryprostatin B + [reduced NADPH-hemoprotein reductase] + O2 | - |
Aspergillus fumigatus | 6-hydroxytryprostatin B + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
tryprostatin B + [reduced NADPH-hemoprotein reductase] + O2 | - |
Aspergillus fumigatus BM939 | 6-hydroxytryprostatin B + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ftmC | - |
Aspergillus fumigatus |
FtmC protein | - |
Aspergillus fumigatus |
General Information | Comment | Organism |
---|---|---|
malfunction | disruption of the ftmC gene leads to substantial accumulation of tryprostatin B and its cyclization product demethoxyfumitremorgin C | Aspergillus fumigatus |