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Literature summary for 1.14.14.114 extracted from

  • Olsson, M.E.; Olofsson, L.M.; Lindahl, A.L.; Lundgren, A.; Brodelius, M.; Brodelius, P.E.
    Localization of enzymes of artemisinin biosynthesis to the apical cells of glandular secretory trichomes of Artemisia annua L (2009), Phytochemistry, 70, 1123-1128.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Artemisia annua
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Source Tissue

Source Tissue Comment Organism Textmining
apical meristem expression of farnesyl diphosphate synthase takes place in apical and sub-apical cells as well as in mesophyl cells while the three enzymes involved in artemisinin biosynthesis, i.e. amorpha-4,11-diene synthase, amorpha-4,11-diene hydroxylase, a cytochrome P450 monooxygenase, and artemisinic aldehyde DELTA11(13) reductase are expressed only in the apical cells Artemisia annua
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General Information

General Information Comment Organism
physiological function the first committed steps in the conversion of farnesyl diphosphate to artemisinin are conducted by amorpha-4,11-diene synthase, amorpha-4,11-diene hydroxylase, a cytochrome P450 monooxygenase, ie. CYP71AV1, and artemisinic aldehyde DELTA11(13) reductase Artemisia annua