BRENDA - Enzyme Database
show all sequences of 1.14.13.7

Multiple roles of component proteins in bacterial multicomponent monooxygenases: phenol hydroxylase and toluene/o-xylene monooxygenase from Pseudomonas sp. OX1

Tinberg, C.E.; Song, W.J.; Izzo, V.; Lippard, S.J.; Biochemistry 50, 1788-1798 (2011)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
additional information
Pseudomonas sp.
only complete enzyme systems containing all three or four protein components are capable of oxidizing phenol. The electron-transfer components exert regulatory effects on substrate oxidation processes taking place at the hydroxylase actives sites, most likely through allostery. The regulatory proteins facilitate the electron-transfer step in the hydrocarbon oxidation cycle in the absence of phenol. Under these conditions, electron consumption is coupled to H2O2 formation in a hydroxylase-dependent manner
?
-
-
-
additional information
Pseudomonas sp. OX1
only complete enzyme systems containing all three or four protein components are capable of oxidizing phenol. The electron-transfer components exert regulatory effects on substrate oxidation processes taking place at the hydroxylase actives sites, most likely through allostery. The regulatory proteins facilitate the electron-transfer step in the hydrocarbon oxidation cycle in the absence of phenol. Under these conditions, electron consumption is coupled to H2O2 formation in a hydroxylase-dependent manner
?
-
-
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Pseudomonas sp.
-
-
-
Pseudomonas sp. OX1
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
additional information
only complete enzyme systems containing all three or four protein components are capable of oxidizing phenol. The electron-transfer components exert regulatory effects on substrate oxidation processes taking place at the hydroxylase actives sites, most likely through allostery. The regulatory proteins facilitate the electron-transfer step in the hydrocarbon oxidation cycle in the absence of phenol. Under these conditions, electron consumption is coupled to H2O2 formation in a hydroxylase-dependent manner
724304
Pseudomonas sp.
?
-
-
-
-
additional information
only complete enzyme systems containing all three or four protein components are capable of oxidizing phenol. The electron-transfer components exert regulatory effects on substrate oxidation processes taking place at the hydroxylase actives sites, most likely through allostery. The regulatory proteins facilitate the electron-transfer step in the hydrocarbon oxidation cycle in the absence of phenol. Under these conditions, electron consumption is coupled to H2O2 formation in a hydroxylase-dependent manner
724304
Pseudomonas sp. OX1
?
-
-
-
-
Cofactor
Cofactor
Commentary
Organism
Structure
[2Fe-2S]-center
under ideal conditions, the hydroxylated product yield is about 50% of the diiron centers, suggesting that the enzyme operates by half-sites reactivity mechanisms
Pseudomonas sp.
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
[2Fe-2S]-center
under ideal conditions, the hydroxylated product yield is about 50% of the diiron centers, suggesting that the enzyme operates by half-sites reactivity mechanisms
Pseudomonas sp.
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
additional information
Pseudomonas sp.
only complete enzyme systems containing all three or four protein components are capable of oxidizing phenol. The electron-transfer components exert regulatory effects on substrate oxidation processes taking place at the hydroxylase actives sites, most likely through allostery. The regulatory proteins facilitate the electron-transfer step in the hydrocarbon oxidation cycle in the absence of phenol. Under these conditions, electron consumption is coupled to H2O2 formation in a hydroxylase-dependent manner
?
-
-
-
additional information
Pseudomonas sp. OX1
only complete enzyme systems containing all three or four protein components are capable of oxidizing phenol. The electron-transfer components exert regulatory effects on substrate oxidation processes taking place at the hydroxylase actives sites, most likely through allostery. The regulatory proteins facilitate the electron-transfer step in the hydrocarbon oxidation cycle in the absence of phenol. Under these conditions, electron consumption is coupled to H2O2 formation in a hydroxylase-dependent manner
?
-
-
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
additional information
only complete enzyme systems containing all three or four protein components are capable of oxidizing phenol. The electron-transfer components exert regulatory effects on substrate oxidation processes taking place at the hydroxylase actives sites, most likely through allostery. The regulatory proteins facilitate the electron-transfer step in the hydrocarbon oxidation cycle in the absence of phenol. Under these conditions, electron consumption is coupled to H2O2 formation in a hydroxylase-dependent manner
724304
Pseudomonas sp.
?
-
-
-
-
additional information
only complete enzyme systems containing all three or four protein components are capable of oxidizing phenol. The electron-transfer components exert regulatory effects on substrate oxidation processes taking place at the hydroxylase actives sites, most likely through allostery. The regulatory proteins facilitate the electron-transfer step in the hydrocarbon oxidation cycle in the absence of phenol. Under these conditions, electron consumption is coupled to H2O2 formation in a hydroxylase-dependent manner
724304
Pseudomonas sp. OX1
?
-
-
-
-
Other publictions for EC 1.14.13.7
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
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Can. J. Microbiol.
60
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742574
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Multistep conversion of creso ...
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Front. Environ. Sci. Eng.
8
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2014
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743073
El-Sayed
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Pseudomonas sp. PT3
J. Microbiol.
52
13-19
2014
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724084
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Arthrobacter sp.
Appl. Microbiol. Biotechnol.
97
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2013
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711022
Izzo
PHK from phenol hydroxylase of ...
Pseudomonas sp., Pseudomonas sp. OX1
Arch. Biochem. Biophys.
505
48-59
2011
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724303
McCormick
Analysis of substrate access t ...
Pseudomonas sp., Pseudomonas sp. OX1
Biochemistry
50
11058-11069
2011
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1
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7
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724304
Tinberg
Multiple roles of component pr ...
Pseudomonas sp., Pseudomonas sp. OX1
Biochemistry
50
1788-1798
2011
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726045
Turek
Isolation and partial characte ...
Comamonas testosteroni
Neuroendocrinol. Lett.
32
137-145
2011
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703338
Zhan
Benzoate catabolite repression ...
Acinetobacter calcoaceticus
Curr. Microbiol.
59
368-373
2009
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703484
Nebe
Quantification of aromatic oxy ...
uncultured microorganism
Environ. Sci. Technol.
43
2029-2034
2009
1
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1
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685427
Viggor
Evaluation of different phenol ...
Pseudomonas fluorescens, Pseudomonas mendocina, Pseudomonas putida
Biodegradation
19
759-769
2008
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3
3
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3
13
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3
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690216
Manasiev
Molecular analysis of phenol-d ...
Cutaneotrichosporon cutaneum, no activity in Escherichia coli, no activity in Escherichia coli JM109, no activity in Lactobacillus acidophilus
Z. Naturforsch. C
63
133-138
2008
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1
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13
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701413
Zhu
-
Molecular cloning, genetic org ...
Alcaligenes faecalis, Alcaligenes faecalis IS-46, Alcaligenes faecalis IS-67, Alcaligenes sp. IS-46
World J. Microbiol. Biotechnol.
24
1687-1695
2008
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2
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1
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15
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17
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17
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7
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701833
Basile
Quantitative assessment of phe ...
uncultured microorganism
Appl. Microbiol. Biotechnol.
78
863-872
2008
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32
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31
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31
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704033
Dong
-
Characterization of phenol-deg ...
Acinetobacter sp. PND-4, Acinetobacter sp. PND-5, Comamonas sp. PND-3, Cupriavidus sp. PND-6, Pseudomonas sp. PND-1, Pseudomonas sp. PND-2
Int. Biodeter. Biodegrad.
62
257-262
2008
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6
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6
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704952
Yemendzhiev
Growth of Trametes versicolor ...
Trametes versicolor 1, Trametes versicolor
J. Ind. Microbiol. Biotechnol.
35
1309-1312
2008
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1
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690215
Gerginova
Influence of various phenolic ...
Cutaneotrichosporon cutaneum, Cutaneotrichosporon cutaneum R57
Z. Naturforsch. C
62
83-86
2007
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13
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13
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1
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671532
Kagle
Phenylacetylene reversibly inh ...
Pseudomonas sp., Pseudomonas sp. CF 600
Appl. Microbiol. Biotechnol.
72
306-315
2006
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1
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8
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12
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-
1
-
-
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-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
671645
Merimaa
Grouping of phenol hydroxylase ...
Pseudomonas sp.
Arch. Microbiol.
186
287-296
2006
-
-
1
-
-
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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-
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
672112
Sazinsky
X-ray structure of a hydroxyla ...
Pseudomonas sp., Pseudomonas sp. OX1
Biochemistry
45
15392-15404
2006
-
-
1
1
-
-
-
-
-
1
-
-
-
7
-
-
-
1
-
-
-
-
2
1
-
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-
-
-
-
-
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-
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
671421
Cafaro
Regiospecificity of two multic ...
Pseudomonas stutzeri, Pseudomonas stutzeri OX1
Appl. Environ. Microbiol.
71
4736-4743
2005
-
-
1
-
-
-
-
8
-
-
-
-
-
8
-
-
-
-
-
-
-
-
13
1
1
-
-
7
-
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
8
-
-
-
-
-
-
-
-
-
-
-
-
13
1
1
-
-
7
-
-
-
-
-
-
-
-
-
-
671422
Cafaro
Mutation of glutamic acid 103 ...
Pseudomonas stutzeri, Pseudomonas stutzeri OX1
Appl. Environ. Microbiol.
71
4744-4750
2005
-
-
1
-
1
-
-
-
-
-
-
6
-
8
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
-
-
1
-
-
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1
1
-
1
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-
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6
-
-
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-
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
672664
Tsai
An isolated Candida albicans T ...
Candida albicans, Candida albicans TL3
Biosci. Biotechnol. Biochem.
69
2358-2367
2005
-
2
-
-
-
-
-
1
-
-
-
2
-
6
-
-
-
-
-
1
2
-
4
-
2
-
-
-
1
-
-
1
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-
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-
1
2
-
4
-
2
-
-
-
1
-
-
-
-
-
-
-
-
-
675732
Kim
Multicomponent phenol hydroxyl ...
Pseudomonas sp.
Lett. Appl. Microbiol.
41
163-168
2005
-
1
1
-
-
-
-
-
-
-
-
2
-
1
-
-
-
-
-
1
-
-
20
-
-
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-
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-
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-
1
-
-
20
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
657596
Cafaro
Phenol hydroxylase and toluene ...
Pseudomonas stutzeri, Pseudomonas stutzeri OX1
Appl. Environ. Microbiol.
70
2211-2219
2004
-
-
-
-
-
-
-
3
-
-
-
2
-
8
-
-
-
-
-
-
-
-
4
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-
-
-
1
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-
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-
4
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1
-
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-
-
-
-
-
-
-
-
658569
Alexievaa
-
Comparison of growth kinetics ...
Cutaneotrichosporon cutaneum
Enzyme Microb. Technol.
34
242-247
2004
-
-
-
-
-
-
-
-
1
-
-
1
-
1
-
-
-
-
-
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-
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1
-
-
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-
-
-
-
-
-
-
-
-
-
-
-
660560
Ahuatzi-Chacon
-
Kinetic study of phenol hydrox ...
Candida tropicalis
World J. Microbiol. Biotechnol.
20
695-702
2004
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
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-
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-
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-
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-
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-
-
-
-
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-
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-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
657449
Enroth
High-resolution structure of p ...
Cutaneotrichosporon cutaneum
Acta Crystallogr. Sect. D
59
1597-1602
2003
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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-
-
-
-
-
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-
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-
-
-
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-
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
658615
Griva
Phenol hydroxylase from Acinet ...
Acinetobacter radioresistens, Acinetobacter radioresistens S13
Eur. J. Biochem.
270
1434-1440
2003
-
-
-
-
-
-
-
-
-
1
-
-
-
9
-
-
-
-
-
1
-
-
-
1
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-
-
-
-
-
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-
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-
-
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-
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-
-
1
-
-
-
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
658619
Divari
The oxygenase component of phe ...
Acinetobacter radioresistens, Acinetobacter radioresistens S13
Eur. J. Biochem.
270
2244-2253
2003
-
-
1
-
-
-
-
-
-
-
4
-
-
7
-
-
1
-
-
-
-
-
16
1
1
1
-
2
1
1
-
1
-
1
-
-
-
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-
-
-
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4
-
-
-
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-
-
-
-
16
1
1
1
-
2
1
1
-
1
-
-
-
-
-
-
658813
Stiborova
Hydroxylation of phenol to cat ...
Candida tropicalis
Gen. Physiol. Biophys.
22
167-179
2003
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
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-
-
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-
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-
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-
-
-
-
-
-
-
-
-
-
-
659881
Jeong
3- and 4-alkylphenol degradati ...
Pseudomonas sp., Pseudomonas sp. KL28
Microbiology
149
3265-3277
2003
-
-
1
-
-
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
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-
-
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-
-
1
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1
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-
-
-
12
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
438790
Cadieux
Biochemical, Mossbauer, and EP ...
Pseudomonas sp., Pseudomonas sp. CF 600
Biochemistry
41
10680-10691
2002
-
-
-
-
-
-
1
-
-
-
-
-
-
11
-
-
1
-
-
-
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-
2
1
-
-
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-
-
-
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-
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-
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1
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
438801
Xu
Studies of the mechanism of ph ...
Cutaneotrichosporon cutaneum
Biochemistry
41
13627-13636
2002
-
-
1
-
1
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
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-
-
-
-
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-
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-
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-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
438800
Xu
Studies of the mechanism of ph ...
Cutaneotrichosporon cutaneum
Biochemistry
40
12369-12378
2001
-
-
1
-
3
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
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-
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-
-
-
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-
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-
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-
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-
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-
-
-
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-
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-
-
-
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-
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
438797
Pessione
Phenol hydroxylase from Acinet ...
Acinetobacter radioresistens
Eur. J. Biochem.
265
549-555
1999
-
-
-
-
-
-
-
1
-
1
2
-
-
6
-
-
1
-
-
-
1
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
2
-
-
-
-
1
-
-
1
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
662875
Teramoto
Characterization of a high-aff ...
Comamonas testosteroni, Comamonas testosteroni R5
Mol. Gen. Genet.
262
552-558
1999
-
-
1
-
-
-
-
-
-
-
-
2
-
9
-
-
-
-
-
-
-
-
20
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
20
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
438791
Enroth
The crystal structure of pheno ...
Cutaneotrichosporon cutaneum
Structure
6
605-617
1998
-
-
1
1
-
-
-
-
-
-
-
-
-
3
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
2
-
-
-
-
-
1
2
1
-
-
-
-
-
-
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-
-
-
-
-
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-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
438792
Hino
-
Phenol hydroxylase cloned from ...
Cupriavidus necator, Cupriavidus necator E2
Microbiology
144
1765-1772
1998
-
-
1
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
438799
Waters
-
Sources and nature of heteroge ...
Cutaneotrichosporon cutaneum
Biotechnol. Appl. Biochem.
25
235-242
1997
-
-
1
-
-
-
-
-
-
-
2
-
-
1
-
-
1
-
-
-
4
-
-
1
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
2
-
-
-
-
1
-
-
4
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
438795
Peelen
Conversion of phenol derivativ ...
Cutaneotrichosporon cutaneum
Eur. J. Biochem.
227
284-291
1995
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
1
-
-
-
1
-
18
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
18
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
438798
Waters
A fermentor culture for produc ...
Cutaneotrichosporon cutaneum
Protein Expr. Purif.
5
534-540
1994
-
-
1
-
-
-
-
-
-
-
1
-
-
3
-
-
1
-
-
-
2
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
2
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
438794
Maeda-Yorita
On the reaction mechanism of p ...
Cutaneotrichosporon cutaneum
J. Biol. Chem.
268
4134-4144
1993
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
438796
Peelen
Fluorine-19 NMR study on the p ...
Cutaneotrichosporon cutaneum
Eur. J. Biochem.
218
345-353
1993
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
438793
Kaelin
Phenol hydroxylase from Tricho ...
Cutaneotrichosporon cutaneum
J. Bacteriol.
174
7112-7120
1992
-
-
1
-
-
-
1
1
-
-
-
-
-
10
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
1
1
1
-
-
-
-
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
438786
Selitz
Phenol hydroxylase from yeast. ...
Cutaneotrichosporon cutaneum
Eur. J. Biochem.
170
343-349
1987
-
-
-
-
-
-
1
-
-
-
-
-
-
3
-
-
1
-
-
-
1
1
1
1
-
-
-
-
-
-
-
1
1
-
-
-
-
-
1
-
-
-
-
1
1
-
-
-
-
-
-
-
-
1
-
-
1
1
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
438789
Mörtberg
In situ and in vitro kinetics ...
Cutaneotrichosporon cutaneum
Biochem. Biophys. Res. Commun.
146
41-46
1987
1
-
-
-
-
-
8
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
10
-
-
-
-
-
-
-
-
1
8
-
-
1
-
-
1
-
-
-
-
8
8
1
-
-
-
-
-
-
-
-
-
-
-
-
10
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
394993
Krug
Degradation of phenolic compou ...
Candida tropicalis
J. Basic Microbiol.
26
271-281
1986
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3
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20
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2
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1
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20
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2
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1
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1
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438782
Detmer
Effect of substrate and pH on ...
Cutaneotrichosporon cutaneum
J. Biol. Chem.
260
5998-6005
1985
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8
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8
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1
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438781
Detmer
Effect of monovalent anions on ...
Cutaneotrichosporon cutaneum
J. Biol. Chem.
259
11265-11272
1984
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2
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1
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438784
Neujahr
Effect of anions, chaotropes, ...
Cutaneotrichosporon cutaneum
Biochemistry
22
580-584
1983
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10
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10
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1
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438785
Neujahr
Phenol hydroxylase from yeast: ...
Cutaneotrichosporon cutaneum
Biochemistry
19
4967-4972
1980
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6
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3
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6
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1
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438780
Kjellen
Immobilization of phenol hydro ...
Cutaneotrichosporon cutaneum
Biotechnol. Bioeng.
21
715-719
1979
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1
1
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438783
Neujahr
Phenol hydroxylase from yeast. ...
Cutaneotrichosporon cutaneum
J. Biol. Chem.
253
8835-8841
1978
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18
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12
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18
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12
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2
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438779
Neujahr
Phenol hydroxylase from yeast. ...
Cutaneotrichosporon cutaneum
Eur. J. Biochem.
58
351-357
1975
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2
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4
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1
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2
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2
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1
1
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438777
Neujahr
Phenol hydroxylase from yeast. ...
Cutaneotrichosporon cutaneum
Eur. J. Biochem.
35
386-400
1973
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18
3
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1
1
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4
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1
1
12
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2
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1
2
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1
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2
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2
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18
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3
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1
1
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1
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1
1
12
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2
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1
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438778
Nakagawa
Phenol hydroxylase ...
Brevibacterium fuscum
Biochim. Biophys. Acta
62
423-426
1962
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2
4
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1
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18
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4
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1
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18
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