Any feedback?
Literature summary for 1.14.13.38 extracted from
- Effect of tetracycline derivates and some cations on the activity of anhydrotetracycline oxygenase (1983), Biotechnol. Lett., 5, 537-542.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| ammonium sulfate | - |
Kitasatospora aureofaciens |  |
| Ca2+ | above 2 mM | Kitasatospora aureofaciens | |
| chlortetracycline | - |
Kitasatospora aureofaciens | |
| Co2+ | - |
Kitasatospora aureofaciens | |
| Cu2+ | - |
Kitasatospora aureofaciens | |
| Fe3+ | - |
Kitasatospora aureofaciens | |
| Mg2+ | above 1 mM | Kitasatospora aureofaciens | |
| Mn2+ | - |
Kitasatospora aureofaciens | |
| Ni2+ | - |
Kitasatospora aureofaciens | |
| oxytetracycline | - |
Kitasatospora aureofaciens | |
| tetracycline | - |
Kitasatospora aureofaciens | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.022 | - |
anhydrotetracycline | - |
Kitasatospora aureofaciens | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | - |
Kitasatospora aureofaciens | 5737 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | increase of activity at 0.1-2 mM | Kitasatospora aureofaciens | |
| Co2+ | increase of activity | Kitasatospora aureofaciens | |
| Cu2+ | increase of activity | Kitasatospora aureofaciens | |
| Fe2+ | increase of activity | Kitasatospora aureofaciens | |
| Fe3+ | increase of activity | Kitasatospora aureofaciens | |
| Mg2+ | increase of activity at 0.1-1 mM | Kitasatospora aureofaciens | |
| Mn2+ | increase of activity | Kitasatospora aureofaciens | |
| Ni2+ | increase of activity | Kitasatospora aureofaciens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Kitasatospora aureofaciens | - |
50/137, UV-light induced mutant of strain 84/25 | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Kitasatospora aureofaciens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| anhydrooxytetracycline + NADPH + O2 | - |
Kitasatospora aureofaciens | ? | - |
? | |
| anhydrotetracycline + NADPH + O2 | - |
Kitasatospora aureofaciens | 12-dehydrotetracycline + NADP+ + H2O | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADPH | - |
Kitasatospora aureofaciens | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
