Activating Compound | Comment | Organism | Structure |
---|---|---|---|
3-Hydroxyanthranilate | induces | Aspergillus niger | |
anthranilate | induces, the enzyme activity increases with an increase in the concentration of anthranilate in the growth medium, optimal amounts of the enzyme are synthesized when the concentration of anthranilate is 1 mg/ml, further increase in the concentration results in a considerable decrease in the growth of the organism as well in the enzyme activity | Aspergillus niger | |
kynurenine | induces | Aspergillus niger | |
L-tryptophan | induces | Aspergillus niger |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
cycloheximide | inhibits the enzyme induction | Aspergillus niger |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aspergillus niger | - |
inducible enzyme | - |
Aspergillus niger | - |
UBC 814 | - |
Aspergillus niger UBC 814 | - |
UBC 814 | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0026 | - |
organism grown on the standard medium with kynurenine | Aspergillus niger |
0.0032 | - |
organism grown on the standard medium with tryptophan | Aspergillus niger |
0.0056 | - |
organism grown on the standard medium with 3-hydroxyanthranilate | Aspergillus niger |
0.0058 | - |
organism grown on the standard medium with anthranilate | Aspergillus niger |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
anthranilate + NADPH + O2 | - |
Aspergillus niger | 2,3-dihydroxybenzoate + NADP+ + NH3 | - |
? | |
anthranilate + NADPH + O2 | - |
Aspergillus niger UBC 814 | 2,3-dihydroxybenzoate + NADP+ + NH3 | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6 | - |
for optimal induction | Aspergillus niger |
8.2 | - |
assay at | Aspergillus niger |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Aspergillus niger |