BRENDA - Enzyme Database
show all sequences of 1.14.13.240

Evolution of ubiquinone biosynthesis multiple proteobacterial enzymes with various regioselectivities to catalyze three contiguous aromatic hydroxylation reactions

Pelosi, L.; Ducluzeau, A.L.; Loiseau, L.; Barras, F.; Schneider, D.; Junier, I.; Pierrel, F.; mSystems 30, e00091 (2016)

Data extracted from this reference:

Organism
Organism
UniProt
Commentary
Textmining
Neisseria meningitidis
E0N696
-
-
Neisseria meningitidis ATCC 13091
E0N696
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
2-(all-trans-polyprenyl)phenol + NADPH + H+ + O2
-
745829
Neisseria meningitidis
3-(all-trans-polyprenyl)benzene-1,2-diol + NADP+ + H2O
-
-
-
?
2-(all-trans-polyprenyl)phenol + NADPH + H+ + O2
-
745829
Neisseria meningitidis ATCC 13091
3-(all-trans-polyprenyl)benzene-1,2-diol + NADP+ + H2O
-
-
-
?
Synonyms
Synonyms
Commentary
Organism
HMPREF0602_0026
-
Neisseria meningitidis
ubiM
-
Neisseria meningitidis
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
2-(all-trans-polyprenyl)phenol + NADPH + H+ + O2
-
745829
Neisseria meningitidis
3-(all-trans-polyprenyl)benzene-1,2-diol + NADP+ + H2O
-
-
-
?
2-(all-trans-polyprenyl)phenol + NADPH + H+ + O2
-
745829
Neisseria meningitidis ATCC 13091
3-(all-trans-polyprenyl)benzene-1,2-diol + NADP+ + H2O
-
-
-
?
General Information
General Information
Commentary
Organism
physiological function
expression of UbiM complements C-1/C-5/C-6 hydroxylation defects in Escherichia coli. Neisseria meningitidis does not contain ubiH, ubiF, ubiI, ubiL, or coq7 genes but possesses instead a single ubiquinone hydroxylase-encoding gene, i.e. UbiM. UbiM may perform all three hydroxylation reactions of the ubiquinone biosynthetic pathway in Neisseria meningitidis
Neisseria meningitidis
General Information (protein specific)
General Information
Commentary
Organism
physiological function
expression of UbiM complements C-1/C-5/C-6 hydroxylation defects in Escherichia coli. Neisseria meningitidis does not contain ubiH, ubiF, ubiI, ubiL, or coq7 genes but possesses instead a single ubiquinone hydroxylase-encoding gene, i.e. UbiM. UbiM may perform all three hydroxylation reactions of the ubiquinone biosynthetic pathway in Neisseria meningitidis
Neisseria meningitidis
Other publictions for EC 1.14.13.240
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
745829
Pelosi
Evolution of ubiquinone biosy ...
Neisseria meningitidis, Neisseria meningitidis ATCC 13091
mSystems
30
e00091
2016
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745289
Hajj Chehade
ubiI, a new gene in Escherich ...
Escherichia coli
J. Biol. Chem.
288
20085-20092
2013
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