Application | Comment | Organism |
---|---|---|
agriculture | treatment of coffee waste with caffeine-degrading microorganisms (either wild type or recombinant) may transform the waste into a valuable by-product, rather than a waste stream, because a caffeine concentration in the waste greater than 1% makes it unsuitable as animal feed or as a biofuel feedstock | Pseudomonas sp. |
Cloned (Comment) | Organism |
---|---|
gene tmuM, genes involved in the caffeine C-8 oxidation pathway are located in a 25.2-kb genomic DNA fragment of CBB1, including cdhABC (coding for caffeine dehydrogenase) and tmuM (coding for TmuM) | Pseudomonas sp. |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
43000 | - |
x * 43000 | Pseudomonas sp. |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
1,3,7-trimethylurate + NADH + H+ + O2 | Pseudomonas sp. | - |
1,3,7-trimethyl-5-hydroxyisourate + NAD+ + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas sp. | I7ASS7 | gene tmuM | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1,3,7-trimethylurate + NADH + H+ + O2 | - |
Pseudomonas sp. | 1,3,7-trimethyl-5-hydroxyisourate + NAD+ + H2O | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 43000 | Pseudomonas sp. |
Synonyms | Comment | Organism |
---|---|---|
NADH-dependent trimethyluric acid monooxygenase | - |
Pseudomonas sp. |
tmuM | - |
Pseudomonas sp. |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | - |
Pseudomonas sp. |
General Information | Comment | Organism |
---|---|---|
metabolism | two distinct caffeine metabolic pathways in bacteria: N-demethylation and C-8 oxidation, the NADH-dependent trimethyluric acid monooxygenase is involved in the latter catalyzing the second step of the C-8 oxidation pathway, overview | Pseudomonas sp. |