Literature summary for 1.14.13.154 extracted from

Chen, Y.; Deng, W.; Wu, J.; Qian, J.; Chu, J.; Zhuang, Y.; Zhang, S.; Liu, W.
Genetic modulation of the overexpression of tailoring genes eryK and eryG leading to the improvement of erythromycin A purity and production in Saccharopolyspora erythraea fermentation (2008), Appl. Environ. Microbiol., 74, 1820-1828.

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Application

Application	Comment	Organism
synthesis	systematically modulating the enzyme amounts of EryK and EryG by integrating additional eryK and eryG copies into the industrial strain Saccharopolyspora erythraea HL3168 E3 significantly enhances the process of biotransformation from erythromycin-D to erythromycin-A, nearly completely eliminates the by-products erythromycin-B and erythromycin-C, and efficiently improves erythromycin-A production and purity at the fermentation stage. In conjunction with other traditional and genetic ways to continuously evaluate the erythromycin-A production system	Saccharopolyspora erythraea

Organism

Organism	UniProt	Comment	Textmining
Saccharopolyspora erythraea	P48635	-	-

Synonyms

Synonyms	Comment	Organism
EryK	-	Saccharopolyspora erythraea

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Release 2023.1 (January 2023)