Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
biphenyl + NADH + H+ + O2 | Enterobacter sp. | - |
(1S,2R)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ | - |
? | |
biphenyl + NADH + H+ + O2 | Enterobacter sp. LY402 | - |
(1S,2R)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ | - |
? | |
additional information | Enterobacter sp. | the strain LY402 shows polychlorinated biphenyls degradation abilities of BphA1, molecular simulation and ligand docking studies, overview | ? | - |
? | |
additional information | Enterobacter sp. LY402 | the strain LY402 shows polychlorinated biphenyls degradation abilities of BphA1, molecular simulation and ligand docking studies, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Enterobacter sp. | - |
isolated from polluted soil | - |
Enterobacter sp. LY402 | - |
isolated from polluted soil | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
biphenyl + NADH + H+ + O2 | - |
Enterobacter sp. | (1S,2R)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ | - |
? | |
biphenyl + NADH + H+ + O2 | - |
Enterobacter sp. LY402 | (1S,2R)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ | - |
? | |
additional information | the strain LY402 shows polychlorinated biphenyls degradation abilities of BphA1, molecular simulation and ligand docking studies, overview | Enterobacter sp. | ? | - |
? | |
additional information | the strain LY402 shows polychlorinated biphenyls degradation abilities of BphA1, molecular simulation and ligand docking studies, overview | Enterobacter sp. LY402 | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | three-dimensional model of LY402-BphA1, overview | Enterobacter sp. |
Synonyms | Comment | Organism |
---|---|---|
BDO | - |
Enterobacter sp. |
BphA1 | - |
Enterobacter sp. |
General Information | Comment | Organism |
---|---|---|
additional information | the alpha-subunit of the iron-sulfur protein of biphenyl 2,3-dioxygenase directly influences catalytic activities and substrate specificity, three-dimensional model of LY402-BphA1, overview. The number and subposition of chlorine substituents influence the polychlorinated biphenyls binding ability of BphA1 significantly. Ser283, Val287, Gly321 and Tyr384 residues in the active site of LY402-BphA1 show high variability, and the space limitation of the active site of BphA1 have negative influence on the polychlorinated biphenyls binding affinity of the enzyme | Enterobacter sp. |