Literature summary for 1.14.12.12 extracted from

Zhang, X.; Qu, Y.; Ma, Q.; Kong, C.; Zhou, H.; Cao, X.; Shen, W.; Shen, E.; Zhou, J.
Production of indirubin from tryptophan by recombinant Escherichia coli containing naphthalene dioxygenase genes from Comamonas sp. MQ (2014), Appl. Biochem. Biotechnol., 172, 3194-3206 .

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Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21(DE3) cells	Comamonas sp. MQ

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
naphthalene + NADH + H+ + O2	Comamonas sp. MQ	-	(1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD+	-	?

Organism

Organism	UniProt	Comment	Textmining
Comamonas sp. MQ	G9IE62	large subunit	-
Comamonas sp. MQ	G9IE63	small subunit	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
indole + NADH + H+ + O2	-	Comamonas sp. MQ	cis-indole-2,3-dihydrodiol + NAD+	-	?
naphthalene + NADH + H+ + O2	-	Comamonas sp. MQ	(1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD+	-	?

Synonyms

Synonyms	Comment	Organism
NAG	-	Comamonas sp. MQ
NDO	-	Comamonas sp. MQ

Cofactor

Cofactor	Comment	Organism	Structure
NADH	-	Comamonas sp. MQ

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Release 2023.1 (January 2023)