BRENDA - Enzyme Database show
show all sequences of 1.14.12.12

Production of indirubin from tryptophan by recombinant Escherichia coli containing naphthalene dioxygenase genes from Comamonas sp. MQ

Zhang, X.; Qu, Y.; Ma, Q.; Kong, C.; Zhou, H.; Cao, X.; Shen, W.; Shen, E.; Zhou, J.; Appl. Biochem. Biotechnol. 172, 3194-3206 (2014)

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
expressed in Escherichia coli BL21(DE3) cells; expressed in Escherichia coli BL21(DE3) cells
Comamonas sp. MQ
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
naphthalene + NADH + H+ + O2
Comamonas sp. MQ
-
(1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD+
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Comamonas sp. MQ
G9IE62
large subunit
-
Comamonas sp. MQ
G9IE63
small subunit
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
indole + NADH + H+ + O2
-
741636
Comamonas sp. MQ
cis-indole-2,3-dihydrodiol + NAD+
-
-
-
?
naphthalene + NADH + H+ + O2
-
741636
Comamonas sp. MQ
(1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD+
-
-
-
?
Cofactor
Cofactor
Commentary
Organism
Structure
NADH
;
Comamonas sp. MQ
Cloned(Commentary) (protein specific)
Commentary
Organism
expressed in Escherichia coli BL21(DE3) cells
Comamonas sp. MQ
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NADH
-
Comamonas sp. MQ
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
naphthalene + NADH + H+ + O2
Comamonas sp. MQ
-
(1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD+
-
-
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
indole + NADH + H+ + O2
-
741636
Comamonas sp. MQ
cis-indole-2,3-dihydrodiol + NAD+
-
-
-
?
naphthalene + NADH + H+ + O2
-
741636
Comamonas sp. MQ
(1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD+
-
-
-
?
Other publictions for EC 1.14.12.12
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
741477
Dutta
Enhanced biodegradation of mi ...
Pseudomonas putida, Pseudomonas putida KD6
3 Biotech
7
365
2017
-
-
-
-
-
-
-
-
-
-
-
2
-
3
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
742329
Ji
Cometabolic degradation of di ...
Comamonas sp. JB
Curr. Microbiol.
74
1411-1416
2017
-
-
-
-
-
-
-
-
-
-
-
1
-
3
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
742718
Ferraro
One enzyme, many reactions st ...
Pseudomonas sp., Pseudomonas sp. C18
IUCrJ
4
648-656
2017
-
-
1
1
-
-
-
-
-
-
-
2
-
2
-
-
1
-
-
-
-
-
16
-
-
-
-
-
-
-
-
2
-
-
-
-
-
1
2
1
-
-
-
-
-
-
-
-
-
2
-
-
-
1
-
-
-
-
16
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
742963
Escalante
Simulation of the bottleneck ...
Pseudomonas putida
J. Chem. Inf. Model.
57
550-561
2017
-
-
-
-
-
-
-
-
-
-
-
2
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
741711
Jouanneau
Dihydroxylation of four- and ...
Sphingomonas sp. CHY-1
Appl. Microbiol. Biotechnol.
100
1253-1263
2016
-
-
1
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
742298
Jin
An integrated approach of bio ...
Rhodococcus sp. ustb-1
Chemosphere
128
307-313
2015
-
-
-
-
-
-
-
-
-
-
-
1
-
3
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
741636
Zhang
Production of indirubin from ...
Comamonas sp. MQ
Appl. Biochem. Biotechnol.
172
3194-3206
2014
-
-
1
-
-
-
-
-
-
-
-
2
-
5
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
1
-
-
-
-
-
2
2
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
742392
Peng
Phytoremediation of phenanthr ...
Pseudomonas putida
Environ. Sci. Technol.
48
12824-12832
2014
-
-
1
-
-
-
-
-
-
-
-
1
-
6
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
743124
Librando
Theoretical approach to the i ...
Pseudomonas putida
J. Mol. Model.
20
2354
2014
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
50
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
50
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
743238
Yang
Distribution of naphthalene d ...
Pseudomonas sp.
Microb. Ecol.
68
785-793
2014
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
724086
Seo
Amino acid substitutions in na ...
Pseudomonas sp., Pseudomonas sp. NCIB 9816-4
Appl. Microbiol. Biotechnol.
97
693-704
2013
-
-
-
1
19
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
19
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
725573
Tondervik
Ralstonia sp. U2 naphthalene d ...
Ralstonia sp., Ralstonia sp. U2
J. Biosci. Bioeng.
113
173-178
2012
-
-
1
-
-
-
-
-
-
-
-
-
-
7
-
-
-
-
-
-
-
-
14
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
14
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
726479
Chopard
-
Naphthalene-dioxygenase cataly ...
Pseudomonas sp., Pseudomonas sp. NCIB 9616-4
RSC Adv.
2
605-615
2012
-
-
1
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
11
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
11
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
695702
Pathak
Biosynthesis of indigo dye by ...
Pseudomonas sp., Pseudomonas sp. HOB1
Appl. Biochem. Biotechnol.
160
1616-1626
2009
-
-
-
-
-
-
-
1
-
-
-
-
-
5
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
685777
McIver
Microbial oxidation of naphtha ...
Escherichia coli
Biotechnol. Prog.
24
593-598
2008
-
1
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
687299
Ohta
Near-IR MCD of the nonheme fer ...
Pseudomonas sp.
J. Am. Chem. Soc.
130
1601-1610
2008
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
688439
Chopard
-
Naphthalene-dioxygenase-cataly ...
Pseudomonas sp.
J. Mol. Catal. B
50
53-60
2008
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
696501
Piskonen
Evaluating the biodegradation ...
Pseudomonas putida, Pseudomonas putida G7
Biodegradation
19
883-895
2008
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
701235
AbuBakr
Enzymatic transformation of hu ...
Pseudomonas putida, Pseudomonas putida G7
Soil Biol. Biochem.
40
2055-2062
2008
-
-
1
-
-
-
-
-
-
-
-
-
-
7
-
-
1
-
-
-
-
1
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
672079
Jouanneau
Characterization of a naphthal ...
Sphingomonas sp.
Biochemistry
45
12380-12391
2006
-
-
1
-
-
-
-
2
-
1
5
-
-
2
-
-
1
-
-
-
-
-
7
2
-
-
-
2
-
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
2
-
1
5
-
-
-
-
1
-
-
-
-
7
2
-
-
-
2
-
-
-
-
-
-
-
-
-
-
673725
Lee
p-hydroxylation reactions cata ...
Pseudomonas sp., Pseudomonas sp. NCIB 9816-4
FEMS Microbiol. Lett.
255
316-320
2006
-
-
1
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
13
-
-
-
-
-
-
-
-
2
-
-
-
-
-
1
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
674304
Ferraro
Structural basis for regiosele ...
Pseudomonas sp., Pseudomonas sp. NCIB 9816-4
J. Bacteriol.
188
6986-6994
2006
-
-
1
1
1
-
-
-
-
-
-
-
-
5
-
-
1
-
-
-
-
-
10
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
1
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
10
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
674252
Gakhar
Structure and increased thermo ...
Rhodococcus sp., Rhodococcus sp. NCIMB12038
J. Bacteriol.
187
7222-7231
2005
-
-
-
1
-
-
-
-
-
-
-
-
-
7
-
-
1
-
-
-
-
-
4
1
-
-
1
-
-
-
-
1
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
4
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
674918
Karlsson
NO binding to naphthalene diox ...
Escherichia coli, Escherichia coli JM109(DE3)
J. Biol. Inorg. Chem.
10
483-489
2005
-
-
-
1
-
-
-
-
-
1
-
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
660531
Boyd
-
Dioxygenase-catalyzed sulfoxid ...
Pseudomonas putida, Pseudomonas putida 8859
Tetrahedron
60
549-559
2004
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
10
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
10
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
658492
Matsui
Naphtho[1,2-b]thiophene degrad ...
Pseudomonas sp., Pseudomonas sp. HKT554
Curr. Microbiol.
46
39-42
2003
-
-
-
-
-
-
-
-
-
-
-
2
-
3
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
660501
Karlsson
Crystal structure of naphthale ...
Pseudomonas sp.
Science
299
1039-1042
2003
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
439105
Malik
Crystallization and preliminar ...
Rhodococcus sp., Rhodococcus sp. NCIMB12038
Acta Crystallogr. Sect. D
58
2173-2174
2002
-
-
-
1
-
-
-
-
-
-
-
-
-
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
439103
Parales
Substrate specifity of naphtha ...
Pseudomonas sp.
J. Bacteriol.
182
1641-1649
2000
-
-
-
-
17
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
17
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
439104
Carredano
Substrate binding site of naph ...
Pseudomonas sp.
J. Mol. Biol.
296
701-712
2000
-
-
-
1
-
-
-
-
-
1
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
439100
Larkin
Purification and characterizat ...
Rhodococcus sp., Rhodococcus sp. NCIMB12038
J. Bacteriol.
181
6200-6204
1999
-
-
-
-
-
-
-
-
-
1
3
-
-
8
-
-
1
-
-
-
1
-
2
2
-
-
-
-
-
-
-
4
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
1
3
-
-
-
-
1
-
-
1
-
2
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
439101
Barriault
Functionality of biphenyl 2,3- ...
Pseudomonas putida, Pseudomonas putida G7
Appl. Microbiol. Biotechnol.
51
592-597
1999
-
-
1
-
-
-
-
-
-
-
2
-
-
7
-
-
-
-
-
-
-
-
6
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
6
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
439102
Lee
Benzene-induced uncoupling of ...
Pseudomonas sp.
J. Bacteriol.
181
2719-2725
1999
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
439099
Lee
Stereospecific oxidation of (R ...
Pseudomonas sp.
Appl. Environ. Microbiol.
63
2067-2070
1997
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
285288
Resnick
Oxidation of 6,7-dihydro-5H-be ...
Pseudomonas sp.
Appl. Environ. Microbiol.
62
1364-1368
1996
-
-
-
-
-
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
439095
Resnick
Regio- and stereospecific oxid ...
Pseudomonas sp.
Appl. Environ. Microbiol.
62
4073-4080
1996
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
439096
Resnick
Regio- and stereospecific oxid ...
Pseudomonas sp.
Appl. Environ. Microbiol.
62
3355-3359
1996
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
439098
Lee
Stereospecific dihydroxylation ...
Pseudomonas sp.
J. Bacteriol.
178
3353-3356
1996
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
439093
Gibson
Desaturation, dioxygenation, a ...
Pseudomonas sp.
J. Bacteriol.
177
2615-2621
1995
-
-
1
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
439094
Torok
Desaturation and oxygenation o ...
Pseudomonas sp.
J. Bacteriol.
177
5799-5805
1995
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
439091
Whited
Oxidation of 2-methoxynaphthal ...
Pseudomonas sp.
Bioorg. Med. chem.
2
727-734
1994
-
-
-
-
-
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
439092
Cidaria
-
A rapid method for naphthalene ...
Pseudomonas fluorescens, Pseudomonas fluorescens NCIMB 40531
Appl. Microbiol. Biotechnol.
41
689-693
1994
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
439090
Swanson
Microbial transformation of be ...
Pseudomonas fluorescens
Appl. Environ. Microbiol.
58
3404-3406
1992
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
740594
Yen
Identification of a new gene, ...
plasmid NAH7
J. Bacteriol.
174
7253-7261
1992
-
-
1
-
-
-
-
-
-
-
1
-
-
5
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
1
-
-
-
437842
Haigler
Purification and properties of ...
Pseudomonas sp.
J. Bacteriol.
172
457-464
1990
1
-
-
-
-
1
5
-
1
1
5
1
-
2
-
-
1
1
-
-
1
2
2
1
-
-
1
-
1
-
-
4
-
-
-
1
-
-
4
-
-
1
-
5
-
-
1
1
5
1
-
-
-
1
-
-
1
2
2
1
-
-
1
-
1
-
-
-
-
-
-
-
-
-
439083
Ensley
Naphthalene dioxygenase from P ...
Pseudomonas sp.
Methods Enzymol.
188
46-52
1990
-
-
-
-
-
1
-
-
1
1
-
1
-
2
-
-
1
-
-
-
-
-
2
-
-
-
-
-
1
-
-
3
-
-
-
-
-
-
3
-
-
1
-
-
-
-
1
1
-
1
-
-
-
1
-
-
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
439084
Kurkela
Cloning, nucleotide sequence a ...
Pseudomonas sp.
Gene
73
355-362
1988
-
-
1
-
-
-
-
-
-
-
-
1
-
3
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
440332
Wackett
Benzylic monooxygenation catal ...
Pseudomonas putida
Biochemistry
27
1360-1367
1988
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
439081
Ensley
Naphthalene dioxygenase: purif ...
Pseudomonas sp., Pseudomonas sp. NCIB 9816
J. Bacteriol.
155
505-511
1983
-
-
-
-
-
2
-
-
1
1
4
2
-
4
-
-
1
-
-
-
1
-
4
1
-
-
-
-
1
-
-
2
-
-
-
-
-
-
2
-
-
2
-
-
-
-
1
1
4
2
-
-
-
1
-
-
1
-
4
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
439088
Ensley
Expression of naphthalene oxid ...
Pseudomonas putida, Pseudomonas putida G7
Science
222
167-169
1983
-
-
1
-
-
-
-
-
-
-
-
-
-
12
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
439085
Ensley
Oxidation of naphthalene by a ...
Pseudomonas sp.
J. Bacteriol.
149
948-954
1982
-
-
-
-
-
2
-
-
1
2
-
1
-
2
-
-
1
-
-
-
-
-
3
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
4
-
-
2
-
-
-
-
1
2
-
1
-
-
-
1
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
439086
Dua
Purification and characterisat ...
Corynebacterium renale
Eur. J. Biochem.
120
461-465
1981
-
-
-
-
-
-
-
2
-
1
3
-
1
2
-
-
1
-
-
-
1
-
1
1
1
-
-
-
1
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
1
3
-
1
-
-
1
-
-
1
-
1
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
439080
Jeffrey
Initial reactions in the oxida ...
Pseudomonas putida 119, Pseudomonas putida
Biochemistry
14
575-584
1975
-
-
-
-
-
-
-
-
-
-
1
2
-
2
-
-
-
1
-
-
-
-
4
-
-
-
-
-
1
-
-
3
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
1
2
-
-
-
-
-
-
-
-
4
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
439087
Catterall
Some properties of the naphtha ...
Pseudomonas sp.
J. Gen. Microbiol.
67
117-124
1971
-
-
-
-
-
2
-
-
-
1
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-