Protein Variants | Comment | Organism |
---|---|---|
additional information | overexpression bypasses the requirement for the positive elongation factor gene BUR1 | Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
dimethyl-histone 3 L-lysine 36 + 2-oxoglutarate + O2 | Saccharomyces cerevisiae | enzyme Rph1 is specific for di- and trimethyl-histone 3 L-lysine36 | methyl-histone 3 L-lysine 36 + succinate + formaldehyde + CO2 | - |
? | |
additional information | Saccharomyces cerevisiae | general function of histone demethylase for histone 3 L-lysine 36 is to promote transcription elongation by antagonizing repressive L-lysine 36 methylation by Set2 methyltransferase | ? | - |
? | |
trimethyl-histone 3 L-lysine 36 + 2-oxoglutarate + O2 | Saccharomyces cerevisiae | enzyme Rph1 is specific for di- and trimethyl-histone 3 L-lysine36 | dimethyl-histone 3 L-lysine 36 + succinate + formaldehyde + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
isoform Rph1 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dimethyl-histone 3 L-lysine 36 + 2-oxoglutarate + O2 | enzyme Rph1 is specific for di- and trimethyl-histone 3 L-lysine36 | Saccharomyces cerevisiae | methyl-histone 3 L-lysine 36 + succinate + formaldehyde + CO2 | - |
? | |
additional information | general function of histone demethylase for histone 3 L-lysine 36 is to promote transcription elongation by antagonizing repressive L-lysine 36 methylation by Set2 methyltransferase | Saccharomyces cerevisiae | ? | - |
? | |
trimethyl-histone 3 L-lysine 36 + 2-oxoglutarate + O2 | enzyme Rph1 is specific for di- and trimethyl-histone 3 L-lysine36 | Saccharomyces cerevisiae | dimethyl-histone 3 L-lysine 36 + succinate + formaldehyde + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Rph1 | - |
Saccharomyces cerevisiae |