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BRENDA support

Literature summary for 1.14.11.68 extracted from

  • Shen, Y.; Guo, X.; Wang, Y.; Qiu, W.; Chang, Y.; Zhang, A.; Duan, X.
    Expression and significance of histone H3K27 demethylases in renal cell carcinoma (2012), BMC Cancer, 12, 470 .
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine in renal cell carcinoma, UTX and JMJD3 transcripts are significantly increased compared to normal tissues. The level of trimethylated H3K27 is lower in cancer tissues compared to normal tissues, but expression of the H3K27 methyltransferase EZH2 is increased Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus
-
Homo sapiens 5634
-

Organism

Organism UniProt Comment Textmining
Homo sapiens O15054 isoform Jmjd3
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Homo sapiens O15550 isoform Utx
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