Literature summary for 1.14.11.67 extracted from

Dorosz, J.; Kristensen, L.H.; Aduri, N.G.; Mirza, O.; Lousen, R.; Bucciarelli, S.; Mehta, V.; Selles-Baiget, S.; Solbak, S.M.O.; Bach, A.; Mesa, P.; Hernandez, P.A.; Montoya, G.; Nguyen, T.T.T.N.; Rand, K.D.; Boesen, T.; Gajhede, M.
Molecular architecture of the Jumonji C family histone demethylase KDM5B (2019), Sci. Rep., 9, 4019 .

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Crystallization (Commentary)

Crystallization (Comment)	Organism
structure of intact multi-domain KDM5B. The PLU region, in the central region of KDM5B, has a curved alpha-helical three-dimensional structure that acts as a rigid linker between the catalytic core and a region comprising four alpha-helices, a loop comprising the PHD2 domain, two large intrinsically disordered loops and the PHD3 domain in close proximity. The dumbbell shaped and curved KDM5B architecture is complementary to the nucleosome surface and has a striking overall similarity to that of the functionally related KDM1A/CoREST complex	Homo sapiens

Crystallization (Comment)

Organism

structure of intact multi-domain KDM5B. The PLU region, in the central region of KDM5B, has a curved alpha-helical three-dimensional structure that acts as a rigid linker between the catalytic core and a region comprising four alpha-helices, a loop comprising the PHD2 domain, two large intrinsically disordered loops and the PHD3 domain in close proximity. The dumbbell shaped and curved KDM5B architecture is complementary to the nucleosome surface and has a striking overall similarity to that of the functionally related KDM1A/CoREST complex

Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9UGL1	-	-

Synonyms

Synonyms	Comment	Organism
JARID1B	-	Homo sapiens
KDM5B	-	Homo sapiens
PLU-1	-	Homo sapiens

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Release 2023.1 (January 2023)