Application | Comment | Organism |
---|---|---|
medicine | ALKBH1 overexpression decreases hepatocellular carcinoma cell viability, induces apoptosis, and decreases migration and invasion. 23779 gain-of-6 mA regions and 11240 loss-of-6 mA regions are differentially identified in hepatocellular carcinoma tissues. The differential gain and loss of 6 mA regions are considerably enriched in intergenic regions. 7% of the differential 6 mA modifications are associated with tumors, with 60 associated with oncogenes and 57 with tumor suppressor genes, and 17 are common to oncogenes and TSGs | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q13686 | bifunctional apurinic/apyrimidinic sites lyase and m6A demethylase, cf. EC 4.2.99.18 | - |
Synonyms | Comment | Organism |
---|---|---|
ALKBH1 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | ALKBH1 overexpression decreases hepatocellular carcinoma cell viability, induces apoptosis, and decreases migration and invasion | Homo sapiens |