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Literature summary for 1.14.11.37 extracted from

  • Gao, W.; Wu, Z.; Sun, J.; Ni, X.; Xia, H.
    Modulation of kanamycin B and kanamycin A biosynthesis in Streptomyces kanamyceticus via metabolic engineering (2017), PLoS ONE, 12, e0181971 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.14.11.37

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli DH5alpha cells Streptomyces kanamyceticus

Metals/Ions

Metals/Ions Comment Organism Structure
Fe2+ required Streptomyces kanamyceticus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
kanamycin B + 2-oxoglutarate + O2 Streptomyces kanamyceticus
-
 2'-dehydrokanamycin A + succinate + NH3 + CO2
-
 ?
kanamycin B + 2-oxoglutarate + O2 Streptomyces kanamyceticus CG305
-
 2'-dehydrokanamycin A + succinate + NH3 + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Streptomyces kanamyceticus Q6L732
-
-
Streptomyces kanamyceticus CG305 Q6L732
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
kanamycin B + 2-oxoglutarate + O2
-
 Streptomyces kanamyceticus 2'-dehydrokanamycin A + succinate + NH3 + CO2
-
 ?
kanamycin B + 2-oxoglutarate + O2
-
 Streptomyces kanamyceticus CG305 2'-dehydrokanamycin A + succinate + NH3 + CO2
-
 ?

Synonyms

Synonyms Comment Organism
kanJ
-
 Streptomyces kanamyceticus