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Literature summary for 1.14.11.32 extracted from

  • Fossati, E.; Narcross, L.; Ekins, A.; Falgueyret, J.P.; Martin, V.J.
    Synthesis of morphinan alkaloids in Saccharomyces cerevisiae (2015), PLoS ONE, 10, e0124459 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Saccharomyces cerevisiae strain GCY1358 Papaver somniferum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
codeine + 2-oxoglutarate + O2 Papaver somniferum
-
morphine + formaldehyde + succinate + CO2
-
?
neopine + 2-oxoglutarate + O2 Papaver somniferum
-
neomorphine + formaldehyde + succinate + CO2
-
?
thebaine + 2-oxoglutarate + O2 Papaver somniferum
-
oripavine + formaldehyde + succinate + CO2
-
?

Organism

Organism UniProt Comment Textmining
Papaver somniferum
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
codeine + 2-oxoglutarate + O2
-
Papaver somniferum morphine + formaldehyde + succinate + CO2
-
?
neopine + 2-oxoglutarate + O2
-
Papaver somniferum neomorphine + formaldehyde + succinate + CO2
-
?
thebaine + 2-oxoglutarate + O2
-
Papaver somniferum oripavine + formaldehyde + succinate + CO2
-
?

Synonyms

Synonyms Comment Organism
codeine-O-demethylase
-
Papaver somniferum
CODM
-
Papaver somniferum