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Literature summary for 1.14.11.3 extracted from
- Substrate specificity of the hydroxylase reaction in which thymidine is converted to thymine ribonucleoside (1972), Biochim. Biophys. Acta, 258, 387-394.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| ascorbate | - |
Neurospora crassa |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| N2 | complete inhibition by exclusion of oxygen | Neurospora crassa | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Fe2+ | - |
Neurospora crassa | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| thymidine + 2-oxoglutarate + O2 | Neurospora crassa | conversion to the ribonucleotide prior to its utilization for DNA synthesis | 5-methyluridine + succinate + CO2 | - |
? | |
| thymidine + 2-oxoglutarate + O2 | Neurospora crassa 1A | conversion to the ribonucleotide prior to its utilization for DNA synthesis | 5-methyluridine + succinate + CO2 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Neurospora crassa | - |
- |
- |
| Neurospora crassa 1A | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| thymidine + 2-oxoglutarate + O2 | conversion to the ribonucleotide prior to its utilization for DNA synthesis | Neurospora crassa | 5-methyluridine + succinate + CO2 | - |
? | |
| thymidine + 2-oxoglutarate + O2 | conversion to the ribonucleotide prior to its utilization for DNA synthesis | Neurospora crassa 1A | 5-methyluridine + succinate + CO2 | - |
? | |
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