Cloned (Comment) | Organism |
---|---|
a human embryonic kidney (HEK) 293 cell line is generated expressing FLAG-tagged PHD2 | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the heat shock protein 90 (HSP90) co-chaperones p23 and FKBP38 interact via a conserved Pro-Xaa-Leu-Glu motif in these proteins with the N-terminal Myeloid Nervy and DEAF-1 (MYND)-type zinc finger of PHD2 | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the heat shock protein 90 (HSP90) co-chaperones p23 and FKBP38 interact via a conserved Pro-Xaa-Leu-Glu motif in these proteins with the N-terminal Myeloid Nervy and DEAF-1 (MYND)-type zinc finger of PHD2 | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PHD2 | - |
Homo sapiens |
prolyl hydroxylase domain protein 2 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | p23 recruits PHD2 to the HSP90 machinery to facilitate HIF-1hydroxylation | Homo sapiens |