Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.14.11.2 extracted from

  • West, C.M.; van der Wel, H.; Wang, Z.A.
    Prolyl 4-hydroxylase-1 mediates O2 signaling during development of Dictyostelium (2007), Development, 134, 3349-3358.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information P4H1 null mutant cells differentiate the basic pre-stalk and pre-spore cell types but exhibit a selectively increased O2 requirement for culmination, from 12% to near or above ambient levels. Overexpression of P4H1 reduces the O2 requirement to below 5%. P4H1-expressing cells accumulate at the anterior end, suggesting that P4H1 enables transcellular signaling by the tip Dictyostelium discoideum

Organism

Organism UniProt Comment Textmining
Dictyostelium discoideum
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information in all cells, expression of an O2-dependent prolyl-4-hydroxylase P4H1 Dictyostelium discoideum
-