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Literature summary for 1.14.11.2 extracted from

  • Hofbauer, K.h.; Gess, B.; Lohaus, C.; Meyer, H.E.; Katschinski, D.; Kurtz, A.
    Oxygen tension regulates the expression of a group of procollagen hydroxylases (2003), Eur. J. Biochem., 270, 4515-4522.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
procollagen L-proline + 2-oxoglutarate + O2 Rattus norvegicus
-
 procollagen trans-4-hydroxy-L-proline + succinate + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-
Rattus norvegicus P54001 alpha-1 subunit
-

Source Tissue

Source Tissue Comment Organism Textmining
A7r5 cell hypoxic atmosphere upregulates P4ha1 mRNA Rattus norvegicus
-
A7r5 cell hypoxic atmosphere upregulates P4ha2 mRNA Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
procollagen L-proline + 2-oxoglutarate + O2
-
 Rattus norvegicus procollagen trans-4-hydroxy-L-proline + succinate + CO2
-
 ?

Synonyms

Synonyms Comment Organism
P4ha1
-
 Rattus norvegicus
P4ha2
-
 Rattus norvegicus
prolyl-4-hydroxylase alpha I
-
 Rattus norvegicus
prolyl-4-hydroxylase alpha II
-
 Rattus norvegicus